相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。P53 and aging: A fresh look at an old paradigm
Masha V. Poyurovsky et al.
AGING-US (2010)
The choice between p53-induced senescence and quiescence is determined in part by the mTOR pathway
Lioubov G. Korotchkina et al.
AGING-US (2010)
Shifting senescence into quiescence by turning up p53
Manuel Serrano
CELL CYCLE (2010)
Survival signalling and apoptosis resistance in glioblastomas: opportunities for targeted therapeutics
Camilla Krakstad et al.
MOLECULAR CANCER (2010)
Paradoxical suppression of cellular senescence by p53
Zoya N. Demidenko et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Genetic alterations and signaling pathways in the evolution of gliomas
Hiroko Ohgaki et al.
CANCER SCIENCE (2009)
Cellular quiescence caused by the Mdm2 inhibitor nutlin-3a
Lioubov G. Korotchkina et al.
CELL CYCLE (2009)
Quercetin promotes degradation of survivin and thereby enhances death-receptor-mediated apoptosis in glioma cells
Markus D. Siegelin et al.
NEURO-ONCOLOGY (2009)
p53 polymorphisms: cancer implications
Catherine Whibley et al.
NATURE REVIEWS CANCER (2009)
Survivin: Key regulator of mitosis and apoptosis and novel target for cancer therapeutics
Alain C. Mita et al.
CLINICAL CANCER RESEARCH (2008)
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
L. Chin et al.
NATURE (2008)
E2F-1 transcriptional activity is a critical determinant of Mdm2 antagonist-induced apoptosis in human tumor cell lines
M. Kitagawa et al.
ONCOGENE (2008)
Malignant astrocytic glioma: genetics, biology, and paths to treatment
Frank B. Furnari et al.
GENES & DEVELOPMENT (2007)
Chemoradiotherapy in malignant glioma: Standard of care and future directions
Roger Stupp et al.
JOURNAL OF CLINICAL ONCOLOGY (2007)
Analysis of the MDM2 antagonist nutlin-3 in human prostate cancer cells
Ian R. Logan et al.
PROSTATE (2007)
Inhibition of p53-murine double minute 2 interaction by nutlin-3A stabilizes p53 and induces cell cycle arrest and apoptosis in Hodgkin lymphoma
Elias Drakos et al.
CLINICAL CANCER RESEARCH (2007)
MDM2 inhibitors for cancer therapy
Lyubomir T. Vassilev
TRENDS IN MOLECULAR MEDICINE (2007)
Regulating the p53 pathway:: in vitro hypotheses, in vivo veritas
Franck Toledo et al.
NATURE REVIEWS CANCER (2006)
Effect of an hdm-2 antagonist peptide inhibitor on cell cycle progression in p53-deficient H1299 human lung carcinoma cells
A. VanderBorght et al.
ONCOGENE (2006)
MDM2 antagonists activate p53 and synergize with genotoxic drugs in B-cell chronic lymphocytic leukemia cells
Llorenc Coll-Mulet et al.
BLOOD (2006)
Small-molecule MDM2 antagonists reveal aberrant p53 signaling in cancer: Implications for therapy
C Tovar et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Clonogenic assay of cells in vitro
Nicolaas A. P. Franken et al.
NATURE PROTOCOLS (2006)
Nongenotoxic activation of the p53 pathway as a therapeutic strategy for multiple myeloma
T Stühmer et al.
BLOOD (2005)
MDM2 antagonists induce p53-dependent apoptosis in AML: implications for leukemia therapy
K Kojima et al.
BLOOD (2005)
Prognostic significance of O6-methylguanine-DNA methyltransferase determined by promoter hypermethylation and immunohistochemical expression in anaplastic gliomas
M Brell et al.
CLINICAL CANCER RESEARCH (2005)
Population-based studies on incidence, survival rates, and genetic alterations in astrocytic and oligodendroglial gliomas
H Ohgaki et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2005)
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
R Stupp et al.
NEW ENGLAND JOURNAL OF MEDICINE (2005)
Polymorphism in wild-type p53 modulates response to chemotherapy in vitro and in vivo
A Sullivan et al.
ONCOGENE (2004)
p53: 25 years after its discovery
LJ Hofseth et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2004)
In vivo activation of the p53 pathway by small-molecule antagonists of MDM2
LT Vassilev et al.
SCIENCE (2004)
Role of cell cycle in mediating sensitivity to radiotherapy
TM Pawlik et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2004)
Adenovirus-mediated transfer of siRNA against survivin induced apoptosis and attenuated tumor cell growth in vitro and in vivo
H Uchida et al.
MOLECULAR THERAPY (2004)
Genetic pathways to glioblastoma:: A population-based study
H Ohgaki et al.
CANCER RESEARCH (2004)
Expression profiling via novel multiplex assay allows rapid assessment of gene regulation in defined signalling pathways
E Eldering et al.
NUCLEIC ACIDS RESEARCH (2003)
Survivin, versatile modulation of cell division and apoptosis in cancer
DC Altieri
ONCOGENE (2003)
Regulation of cellular senescence by p53
K Itahana et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2001)
MDM2 inhibits p300-mediated p53 acetylation and activation by forming a ternary complex with the two proteins
E Kobet et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
分享论文
