4.6 Article

PanSNPdb: The Pan-Asian SNP Genotyping Database

期刊

PLOS ONE
卷 6, 期 6, 页码 -

出版社

PUBLIC LIBRARY SCIENCE
DOI: 10.1371/journal.pone.0021451

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资金

  1. National Center for Genetic Engineering and Biotechnology
  2. National Science and Technology Development Agency (NSTDA) through the National Center for Genetic Engineering and Biotechnology (BIOTEC)
  3. National Science Foundation of China [30971577]
  4. Science and Technology Commission of Shanghai Municipality [09ZR1436400, 11QA1407600]
  5. Bill and Melinda Gates Foundation under the Grand Challenges Explorations Initiative
  6. KRIBB Research Initiative
  7. Korean Ministry of Education, Science and Technology (MEST) [2010-0029345]
  8. MOST
  9. KRIBB internal fund of South Korea
  10. Thailand Research Fund (TRF)
  11. Center of Excellence in Molecular Genetics of Cancer and Human Diseases, Chulalongkorn University
  12. National Research Council of Science & Technology (NST), Republic of Korea [KGM0411123] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
  13. National Research Foundation of Korea [2010-0029345] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

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The HUGO Pan-Asian SNP consortium conducted the largest survey to date of human genetic diversity among Asians by sampling 1,719 unrelated individuals among 71 populations from China, India, Indonesia, Japan, Malaysia, the Philippines, Singapore, South Korea, Taiwan, and Thailand. We have constructed a database (PanSNPdb), which contains these data and various new analyses of them. PanSNPdb is a research resource in the analysis of the population structure of Asian peoples, including linkage disequilibrium patterns, haplotype distributions, and copy number variations. Furthermore, PanSNPdb provides an interactive comparison with other SNP and CNV databases, including HapMap3, JSNP, dbSNP and DGV and thus provides a comprehensive resource of human genetic diversity. The information is accessible via a widely accepted graphical interface used in many genetic variation databases. Unrestricted access to PanSNPdb and any associated files is available at: http://www4a.biotec.or.th/PASNP.

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