相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Mammalian Target of Rapamycin: Its Role in Early Neural Development and in Adult and Aged Brain Function
Carla Garza-Lombo et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2016)
mTOR and cancer: many loops in one pathway
Alejo Efeyan et al.
CURRENT OPINION IN CELL BIOLOGY (2010)
Regulation of mTOR Complex 1 (mTORC1) by Raptor Ser(863) and Multisite Phosphorylation
Kathryn G. Foster et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Requirement of the mTOR Kinase for the Regulation of Maf1 Phosphorylation and Control of RNA Polymerase III-dependent Transcription in Cancer Cells
Boris Shor et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Mammalian Target of Rapamycin (mTOR): Conducting the Cellular Signaling Symphony
Kathryn G. Foster et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Integrating titania enrichment, iTRAQ labeling, and Orbitrap CID-HCD for global identification and quantitative analysis of phosphopeptides
Jiang Wu et al.
PROTEOMICS (2010)
HTAPP: High-throughput autonomous proteomic pipeline
Kebing Yu et al.
PROTEOMICS (2010)
mTORC1-Mediated Cell Proliferation, But Not Cell Growth, Controlled by the 4E-BPs
Ryan J. O. Dowling et al.
SCIENCE (2010)
CDC25B Mediates Rapamycin-induced Oncogenic Responses in Cancer Cells
Run-qiang Chen et al.
CANCER RESEARCH (2009)
Not all substrates are treated equally Implications for mTOR, rapamycin-resistance and cancer therapy
Andrew Y. Choo et al.
CELL CYCLE (2009)
Mammalian target of rapamycin complex 1: Signalling inputs, substrates and feedback mechanisms
E. A. Dunlop et al.
CELLULAR SIGNALLING (2009)
mTOR and the control of whole body metabolism
Pazit Polak et al.
CURRENT OPINION IN CELL BIOLOGY (2009)
The phosphoproteomics data explosion
Simone Lemeer et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2009)
Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis
Alexandre Huber et al.
GENES & DEVELOPMENT (2009)
Increased Confidence in Large-Scale Phosphoproteomics Data by Complementary Mass Spectrometric Techniques and Matching of Phosphopeptide Data Sets
Maria P. Alcolea et al.
JOURNAL OF PROTEOME RESEARCH (2009)
A New Approach for Quantitative Phosphoproteomic Dissection of Signaling Pathways Applied to T Cell Receptor Activation
Vinh Nguyen et al.
MOLECULAR & CELLULAR PROTEOMICS (2009)
Molecular mechanisms of mTOR-mediated translational control
Xiaoju Max Ma et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2009)
Integrated platform for manual and high-throughput statistical validation of tandem mass spectra
Kebing Yu et al.
PROTEOMICS (2009)
PeptideDepot: Flexible relational database for visual analysis of quantitative proteomic data and integration of existing protein information
Kebing Yu et al.
PROTEOMICS (2009)
Analytical strategies for phosphoproteomics
Tine E. Thingholm et al.
PROTEOMICS (2009)
New Insights into mTOR Signaling: mTORC2 and Beyond
Dario R. Alessi et al.
SCIENCE SIGNALING (2009)
The Pharmacology of mTOR Inhibition
David A. Guertin et al.
SCIENCE SIGNALING (2009)
Hepatic translation control in the late-gestation fetal rat
Philip A. Gruppuso et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2008)
Regulation of proline-rich Akt substrate of 40 kDa (PRAS40) function by mammalian target of rapamycin complex 1 (mTORC1)-mediated phosphorylation
Lifu Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Solid Tumor Proteome and Phosphoproteome Analysis by High Resolution Mass Spectrometry
Sara Zanivan et al.
JOURNAL OF PROTEOME RESEARCH (2008)
Phosphoproteomic analysis of human brain by calcium phosphate precipitation and mass spectrometry
Qiangwei Xia et al.
JOURNAL OF PROTEOME RESEARCH (2008)
Quantitative Analysis of Brain Nuclear Phosphoproteins Identifies Developmentally Regulated Phosphorylation Events
Lujian Liao et al.
JOURNAL OF PROTEOME RESEARCH (2008)
Successive and selective release of phosphorylated peptides captured by hydroxy acid-modified metal oxide chromatography
Yutaka Kyono et al.
JOURNAL OF PROTEOME RESEARCH (2008)
The SCX/IMAC enrichment approach for global phosphorylation analysis by mass spectrometry
Judit Villen et al.
NATURE PROTOCOLS (2008)
Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation
Andrew Y. Choo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography
Guanghui Han et al.
PROTEOMICS (2008)
Quantitative time-resolved phosphoproteomic analysis of mast cell signaling
Lulu Cao et al.
JOURNAL OF IMMUNOLOGY (2007)
Phosphopeptide enrichment by aliphatic hydroxy acid-modified metal oxide chromatography for nano-LC-MS/MS in proteomics applications
Naoyuki Sugiyama et al.
MOLECULAR & CELLULAR PROTEOMICS (2007)
Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40
Emilie Vander Haar et al.
NATURE CELL BIOLOGY (2007)
Large-scale phosphorylation analysis of mouse liver
Judit Villen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks
Jesper V. Olsen et al.
CELL (2006)
A probability-based approach for high-throughput protein phosphorylation analysis and site localization
Sean A. Beausoleil et al.
NATURE BIOTECHNOLOGY (2006)
Selective zirconium dioxide-based enrichment of phosphorylated peptides for mass spectrometric analysis
HK Kweon et al.
ANALYTICAL CHEMISTRY (2006)
TOR signaling in growth and metabolism
S Wullschleger et al.
CELL (2006)
Highly selective enrichment of phosphorylated peptides using titanium dioxide
Tine E. Thingholm et al.
NATURE PROTOCOLS (2006)
Phosphoproteomic analysis of rat liver by high capacity IMAC and LC-MS/MS
K Moser et al.
JOURNAL OF PROTEOME RESEARCH (2006)
TOR signaling in growth and metabolism
Stephan Wullschleger et al.
CELL (2006)
mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events
MK Holz et al.
CELL (2005)
Enrichment of phosphorylated proteins and peptides from complex mixtures using metal oxide/hydroxide affinity chromatography (MOAC)
F Wolschin et al.
PROTEOMICS (2005)
Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules
Y Zhang et al.
MOLECULAR & CELLULAR PROTEOMICS (2005)
Highly selective enrichment of phosphorylated peptides from peptide mixtures using titanium dioxide microcolumns
MR Larsen et al.
MOLECULAR & CELLULAR PROTEOMICS (2005)
The regulation of hepatic protein synthesis during fasting in the rat
P Anand et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Automated immobilized metal affinity chromatography/nano-liquid chromatography/electrospray ionization mass spectrometry platform for profiling protein phosphorylation sites
SB Ficarro et al.
RAPID COMMUNICATIONS IN MASS SPECTROMETRY (2005)
Thr2446 is a novel mammalian target of rapamycin (mTOR) phosphorylation site regulated by nutrient status
SWY Cheng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Large-scale characterization of HeLa cell nuclear phosphoproteins
SA Beausoleil et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Phosphoproteome analysis of mouse liver using immobilized metal affinity purification and linear ion trap mass spectrometry
WH Jin et al.
RAPID COMMUNICATIONS IN MASS SPECTROMETRY (2004)
Characterization of eIF3k - A newly discovered subunit of mammalian translation initiation factor eIF3
GL Mayeur et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2003)
The mammalian target of rapamycin (mTOR) partner, raptor, binds the mTOR substrates p70 S6 kinase and 4E-BP1 through their TOR signaling (TOS) motif
H Nojima et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Profiling of tyrosine phosphorylation pathways in human cells using mass spectrometry
AR Salomon et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
A possible linkage between AMP-activated protein kinase (AMPK) and mammalian target of rapamycin (mTOR) signalling pathway
N Kimura et al.
GENES TO CELLS (2003)
Identification of TOR signaling complexes: more TORC for the cell growth engine
RT Abraham
CELL (2002)
Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control
R Loewith et al.
MOLECULAR CELL (2002)
A mass spectrometry-based proteomic approach for identification of serine/threonine-phosphorylated proteins by enrichment with phospho-specific antibodies - Identification of a novel protein, Frigg, as a protein kinase A substrate
M Gronborg et al.
MOLECULAR & CELLULAR PROTEOMICS (2002)
A novel method to identify protein kinase substrates:: eEF2 kinase is phosphorylated and inhibited by SAPK4/p38δ
A Knebel et al.
EMBO JOURNAL (2001)
The rapamycin-sensitive signal transduction pathway as a target for cancer therapy
M Hidalgo et al.
ONCOGENE (2000)