相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Towards a genome-scale kinetic model of cellular metabolism
Kieran Smallbone et al.
BMC SYSTEMS BIOLOGY (2010)
Predicted Functions of MdmX in Fine-Tuning the Response of p53 to DNA Damage
Sohyoung Kim et al.
PLOS COMPUTATIONAL BIOLOGY (2010)
Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity
Ludmila Pawlikowska et al.
AGING CELL (2009)
Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C-elegans
Eric L. Greer et al.
AGING CELL (2009)
Simulation of large-scale rule-based models
Joshua Colvin et al.
BIOINFORMATICS (2009)
Jalview Version 2-a multiple sequence alignment editor and analysis workbench
Andrew M. Waterhouse et al.
BIOINFORMATICS (2009)
Effects of Recombination on Complex Regulatory Circuits
Olivier C. Martin et al.
GENETICS (2009)
The Transcription of FOXO Genes Is Stimulated by FOXO3 and Repressed by Growth Factors
Ahmed Essaghir et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
MDM2 Acts Downstream of p53 as an E3 Ligase to Promote FOXO Ubiquitination and Degradation
Wei Fu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
The Phosphotyrosine Interactome of the Insulin Receptor Family and Its Substrates IRS-1 and IRS-2
Stefan Hanke et al.
MOLECULAR & CELLULAR PROTEOMICS (2009)
Cell cycle regulation by feed-forward loops coupling transcription and phosphorylation
Attila Csikasz-Nagy et al.
MOLECULAR SYSTEMS BIOLOGY (2009)
How to deal with large models?
William S. Hlavacek
MOLECULAR SYSTEMS BIOLOGY (2009)
Signalling through RHEB-1 mediates intermittent fasting-induced longevity in C-elegans
Sakiko Honjoh et al.
NATURE (2009)
Cell fate decision mediated by p53 pulses
Xiao-Peng Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Association of FOXO3A variation with human longevity confirmed in German centenarians
Friederike Flachsbart et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Insulin and JNK: optimizing metabolic homeostasis and lifespan
Jason Karpac et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2009)
Detection of stoichiometric inconsistencies in biomolecular models
Albert Gevorgyan et al.
BIOINFORMATICS (2008)
Explaining oscillations and variability in the p53-Mdm2 system
Carole J. Proctor et al.
BMC SYSTEMS BIOLOGY (2008)
Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans
Jennifer M. A. Tullet et al.
CELL (2008)
FoxO transcription factors in the maintenance of cellular homeostasis during aging
Dervis A. M. Salih et al.
CURRENT OPINION IN CELL BIOLOGY (2008)
Foxo3 is essential for the regulation of ataxia telangiectasia mutated and oxidative stress-mediated homeostasis of hematopoietic stem cells
Safak Yalcin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Stochastic modelling of nucleocytoplasmic oscillations of the transcription factor Msn2 in yeast
Didier Gonze et al.
JOURNAL OF THE ROYAL SOCIETY INTERFACE (2008)
Oscillations and bistability in the stochastic model of p53 regulation
Krzysztof Puszynski et al.
JOURNAL OF THEORETICAL BIOLOGY (2008)
Arginine Methylation of FOXO Transcription Factors Inhibits Their Phosphorylation by Akt
Kazuyuki Yamagata et al.
MOLECULAR CELL (2008)
A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology
Markus J. Herrgard et al.
NATURE BIOTECHNOLOGY (2008)
ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation
Jer-Yen Yang et al.
NATURE CELL BIOLOGY (2008)
Functional interaction between FOXO3a and ATM regulates DNA damage response
Wen-Bin Tsai et al.
NATURE CELL BIOLOGY (2008)
Kinetic Monte Carlo method for rule-based modeling of biochemical networks
Jin Yang et al.
PHYSICAL REVIEW E (2008)
Forkhead transcription factors and ageing
L. Partridge et al.
ONCOGENE (2008)
The role of FoxO in the regulation of metabolism
D. N. Gross et al.
ONCOGENE (2008)
Structure/function relationships underlying regulation of FOXO transcription factors
T. Obsil et al.
ONCOGENE (2008)
FOXO-binding partners: it takes two to tango
K. E. van der Vos et al.
ONCOGENE (2008)
FOXOs, cancer and regulation of apoptosis
Z. Fu et al.
ONCOGENE (2008)
Identification of Direct Target Genes Using Joint Sequence and Expression Likelihood with Application to DAF-16
Ron X. Yu et al.
PLOS ONE (2008)
Mathematical modeling identifies Smad nucleocytoplasmic shuttling as a dynamic signal-interpreting system
Bernhard Schmierer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
FOXO3A genotype is strongly associated with human longevity
Bradley J. Wilicox et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Structural basis for DNA recognition by FoxO1 and its regulation by posttranslational modification
Michael M. Brent et al.
STRUCTURE (2008)
FoxO3 controls autophagy in skeletal muscle in vivo
Cristina Mammucari et al.
CELL METABOLISM (2007)
Crystal structure of the human FOXO3a-DBD/DNA complex suggests the effects of post-translational modification
Kuang-Lei Tsai et al.
NUCLEIC ACIDS RESEARCH (2007)
The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor
Eric L. Greer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C-elegans
Eric L. Greer et al.
CURRENT BIOLOGY (2007)
A Foxo/Notch pathway controls myogenic differentiation and fiber type specification
Tadahiro Kitamura et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
SIRT1 gene, age-related diseases, and mortality:: The Leiden 85-plus Study
Maris Kuningas et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2007)
Nucleocytoplasmic oscillations of the yeast transcription factor Msn2: Evidence for periodic PKA activation
Cecilia Garmendia-Torres et al.
CURRENT BIOLOGY (2007)
PHA-4/Foxa mediates diet-restriction-induced longevity of C-elegans
Siler H. Panowski et al.
NATURE (2007)
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage
Shuhei Matsuoka et al.
SCIENCE (2007)
An in silico model of the ubiquitin-proteasome system that incorporates normal homeostasis and age-related decline
Carole J. Proctor et al.
BMC SYSTEMS BIOLOGY (2007)
High-resolution dynamics of the transcriptional response to nutrition in Drosophila:: a key role for dFOXO
Boris Gershman et al.
PHYSIOLOGICAL GENOMICS (2007)
Mitogen-activated protein kinases, Erk and p38, phosphorylate and regulate Foxo1
Sachie Asada et al.
CELLULAR SIGNALLING (2007)
Global reconstruction of the human metabolic network based on genomic and bibliomic data
Natalie C. Duarte et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Evolutionary conservation of regulated longevity assurance mechanisms
Joshua J. McElwee et al.
GENOME BIOLOGY (2007)
E2F-1 regulates expression of FOXO1 and FOXO3a
Katrin Nowak et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION (2007)
Stressing the role of FoxO proteins in lifespan and disease
Armando van der Horst et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
COPASI- A COmplex PAthway SImulator
Stefan Hoops et al.
BIOINFORMATICS (2006)
CDK2-dependent phosphorylation of FOXO1 as an apoptotic response to DNA damage
Haojie Huang et al.
SCIENCE (2006)
FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP
Armando van der Horst et al.
NATURE CELL BIOLOGY (2006)
Challenges to be faced in the reconstruction of metabolic networks from public databases
M. G. Poolman et al.
IEE PROCEEDINGS SYSTEMS BIOLOGY (2006)
A FoxO-Smad synexpression group in human keratinocytes
Roger R. Gomis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Multiple roles of FOXO transcription factors in mammalian cells point to multiple roles in cancer
Karen C. Arden
EXPERIMENTAL GERONTOLOGY (2006)
A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span
Maria K. Lehtinen et al.
CELL (2006)
Tools for the SBML community
CS Gillespie et al.
BIOINFORMATICS (2006)
RUNX3 cooperates with FoxO3a to induce apoptosis in gastric cancer cells
Y Yamamura et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Identification of direct DAF-16 targets controlling longevity, metabolism and diapause by chromatin immunoprecipitation
SW Oh et al.
NATURE GENETICS (2006)
Coordination and communication between the p53 and IGF-1-AKT-TOR signal transduction pathways
AJ Levine et al.
GENES & DEVELOPMENT (2006)
FOXO transcription factors at the interface between longevity and tumor suppression
EL Greer et al.
ONCOGENE (2005)
Transcriptional feedback control of insulin receptor by dFOXO/FOXO1
O Puig et al.
GENES & DEVELOPMENT (2005)
FoxO1 protects against pancreatic β cell failure through NeuroD and MafA induction
YI Kitamura et al.
CELL METABOLISM (2005)
Acetylation of Foxo1 alters its DNA-binding ability and sensitivity to phosphorylation
H Matsuzaki et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Signaling through receptors and scaffolds: Independent interactions reduce combinatorial complexity
NM Borisov et al.
BIOPHYSICAL JOURNAL (2005)
Integrative model of the response of yeast to osmotic shock
E Klipp et al.
NATURE BIOTECHNOLOGY (2005)
The p38 signal transduction pathway participates in the oxidative stress-mediated translocation of DAF-16 to Caenorhabditis elegans nuclei
M Kondo et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2005)
Nuclear trapping of the forkhead transcription factor FoxO1 via Sirt-dependent deacetylation promotes expression of glucogenetic genes
D Frescas et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
JNK extends life span and limits growth by antagonizing cellular and organism-wide responses to insulin signaling
MC Wang et al.
CELL (2005)
JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16
SW Oh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
IκB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a
MCT Hu et al.
CELL (2004)
Integration of Smad and Forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation
J Seoane et al.
CELL (2004)
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
A Brunet et al.
SCIENCE (2004)
Mammalian SIRT1 represses forkhead transcription factors
MC Motta et al.
CELL (2004)
FoxO3a regulates erythroid differentiation and induces BTG1, an activator of protein arginine methyl transferase 1
WJ Bakker et al.
JOURNAL OF CELL BIOLOGY (2004)
The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span
K Jia et al.
DEVELOPMENT (2004)
The interaction between FOXO and SIRT1: tipping the balance towards survival
ME Giannakou et al.
TRENDS IN CELL BIOLOGY (2004)
Nutrient availability regulates SIRT1 through a forkhead-dependent pathway
S Nemoto et al.
SCIENCE (2004)
FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK
MAG Essers et al.
EMBO JOURNAL (2004)
Long-lived Drosophila with overexpressed dFOXO in adult fat body
ME Giannakou et al.
SCIENCE (2004)
FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2SIRT1
A van der Horst et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity
H Daitoku et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Gene expression profile of long-lived Ames dwarf mice and Little mice
D Amador-Noguez et al.
AGING CELL (2004)
BioNetGen: software for rule-based modeling of signal transduction based on the interactions of molecular domains
ML Blinov et al.
BIOINFORMATICS (2004)
Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body
DS Hwangbo et al.
NATURE (2004)
The ins and outs of FoxO shuttling: mechanisms of FoxO translocation and transcriptional regulation
LP van der Heide et al.
BIOCHEMICAL JOURNAL (2004)
Shared transcriptional signature in Caenorhabditis elegans dauer larvae and long-lived daf-2 mutants implicates detoxification system in longevity assurance
JJ McElwee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Oscillations in NF-κB signaling control the dynamics of gene expression
DE Nelson et al.
SCIENCE (2004)
Insulin-induced phosphorylation of FKHR (Foxo1) targets to proteasomal degradation
H Matsuzaki et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
FoxO6, a novel member of the FoxO class of transcription factors with distinct shuttling dynamics
FMJ Jacobs et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Life extension via dietary restriction is independent of the Ins/IGF-1 signalling pathway in Caenorhabditis elegans
K Houthoofd et al.
EXPERIMENTAL GERONTOLOGY (2003)
FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons
J Gilley et al.
JOURNAL OF CELL BIOLOGY (2003)
Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans
CT Murphy et al.
NATURE (2003)
DAF-16 target genes that control C-elegans life-span and metabolism
SS Lee et al.
SCIENCE (2003)
Hepatocyte nuclear factor-4 is a novel downstream target of insulin via FKHR as a signal-regulated transcriptional inhibitor
K Hirota et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Transcriptional outputs of the Caenorhabditis elegans forkhead protein DAF-16
J McElwee et al.
AGING CELL (2003)
Nutritional and hormonal factors control the gene expression of FoxOs, the mammalian homologues of DAF-16
M Imae et al.
JOURNAL OF MOLECULAR ENDOCRINOLOGY (2003)
Cellerator: extending a computer algebra system to include biochemical arrows for signal transduction simulations
BE Shapiro et al.
BIOINFORMATICS (2003)
Towards an e-biology of ageing: integrating theory and data
TBL Kirkwood et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2003)
The systems biology markup language (SBML):: a medium for representation and exchange of biochemical network models
M Hucka et al.
BIOINFORMATICS (2003)
Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes
K Ashrafi et al.
NATURE (2003)
Phosphorylation of serine 256 suppresses transactivation by FKHR (FOXO1) by multiple mechanisms - Direct and indirect effects on nuclear/cytoplasmic shuttling and DNA binding
XH Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
A mathematical model of metabolic insulin signaling pathways
AR Sedaghat et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2002)
Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress
GJPL Kops et al.
NATURE (2002)
The forkhead transcription factor FoxO regulates transcription of p27Kip1 and bim in response to IL-2
M Stahl et al.
JOURNAL OF IMMUNOLOGY (2002)
Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion
G Rena et al.
EMBO JOURNAL (2002)
DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein
H Tran et al.
SCIENCE (2002)
Defects of the insulin receptor substrate (IRS) system in human metabolic disorders
G Sesti et al.
FASEB JOURNAL (2001)
Ligand-dependent interaction of estrogen receptor-α with members of the forkhead transcription factor family
ER Schuur et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Forkhead homologue in rhabdomyosarcoma functions as a bifunctional nuclear receptor-interacting protein with both coactivator and corepressor functions
HH Zhao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
STOCHSIM:: modelling of stochastic biomolecular processes
N Le Novère et al.
BIOINFORMATICS (2001)
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
HA Tissenbaum et al.
NATURE (2001)
Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)
A Brunet et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Forkhead transcription factor FKHR-L1 modulates cytokine-dependent transcriptional regulation of p27KIP1
PF Dijkers et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1
PF Dijkers et al.
CURRENT BIOLOGY (2000)
T-Coffee: A novel method for fast and accurate multiple sequence alignment
C Notredame et al.
JOURNAL OF MOLECULAR BIOLOGY (2000)
AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1
RH Medema et al.
NATURE (2000)