相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Single pancreatic beta cells co-express multiple islet hormone genes in mice
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Unique splicing pattern of the TCF7L2 gene in human pancreatic islets
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Decreased TCF7L2 protein levels in type 2 diabetes mellitus correlate with downregulation of GIP- and GLP-1 receptors and impaired beta-cell function
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HUMAN MOLECULAR GENETICS (2009)
The FTO Obesity Gene. Genotyping and Gene Expression Analysis in Morbidly Obese Patients
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miR-375 maintains normal pancreatic α- and β-cell mass
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TCF7L2 expression in diabetic patients undergoing bariatric surgery
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A Mouse Model for the Metabolic Effects of the Human Fat Mass and Obesity Associated FTO Gene
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Fatty acids and glucolipotoxicity in the pathogenesis of Type 2 diabetes
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In vitro proliferation of cells derived from adult human β-cells revealed by cell-lineage tracing
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Gene expression of purified β-cell tissue obtained from human pancreas with laser capture microdissection
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Increased interleukin (IL)-1β messenger ribonucleic acid expression in β-cells of individuals with type 2 diabetes and regulation of IL-1β in human islets by glucose and autostimulation
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Proliferation of sorted human and rat beta cells
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被撤回的出版物: Transcription factor 7-like 2 regulates beta-cell survival and function in human pancreatic islets(Retracted article. See vol. 66, pg. 1729, 2017)
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The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase
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JOURNAL OF CLINICAL INVESTIGATION (2007)
A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants
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Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
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SCIENCE (2007)
Expression of ectonucleotide pyrophosphate phosphodiesterase and peroxisome proliferator activated receptor gamma in morbidly obese patients
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A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
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The role of α-cell dysregulation in fasting and postprandial hyperglycemia in type 2 diabetes and therapeutic implications
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Screening of 134 single nucleotide polymorphisms (SNPs) previously associated with type 2 diabetes replicates association with 12 SNPs in nine genes
Cristen J. Willer et al.
DIABETES (2007)
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes
Eleftheria Zeggini et al.
SCIENCE (2007)
Loss of ARNT/HIF1β mediates altered gene expression and pancreatic-islet dysfunction in human type 2 diabetes
JE Gunton et al.
CELL (2005)
β-Cell secretory products activate α-cell ATP-dependent potassium channels to inhibit glucagon release
I Franklin et al.
DIABETES (2005)
Haplotype structure and genotype-phenotype correlations of the sulfonylurea receptor and the islet ATP-sensitive potassium channel gene region
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DIABETES (2004)
Activating mutations in the gene encoding the ATP-sensitive potassium-channel subunit Kir6.2 and permanent neonatal diabetes
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NEW ENGLAND JOURNAL OF MEDICINE (2004)
Impaired intestinal proglucagon processing in mice lacking prohormone convertase 1
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ENDOCRINOLOGY (2004)
Structural and functional abnormalities in the islets isolated from type 2 diabetic subjects
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An insulin-degrading enzyme inhibitor decreases amylin degradation, increases amylin-induced cytotoxicity, and increases amyloid formation in insulinoma cell cultures
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DIABETES (2003)
Insulin-degrading enzyme regulates the levels of insulin, amyloid β-protein, and the β-amyloid precursor protein intracellular domain in vivo
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Large-scale association studies of variants in genes encoding the pancreatic β-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes
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Identification and purification of functional human β-cells by a new specific zinc-fluorescent probe
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Degradation of amylin by insulin-degrading enzyme
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