相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。A role for SIRT1 in cell growth and chemoresistance in prostate cancer PC3 and DU145 cells
Keitaro Kojima et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Localization of mouse mitochondrial SIRT proteins: Shift of SIRT3 to nucleus by co-expression with SIRT5
Yasuhiko Nakamura et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Sirt2 interacts with 14-3-3 β/γ and down-regulates the activity of p53
Yun-Hye Jin et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Inhibition of transcriptional activity of c-JUN by SIRT1
Zhanguo Gao et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Therapeutic role of sirtuins in neurodegenerative disease
Tiago Fleming Outeiro et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2008)
Interactions between SIRT1 and AP-1 reveal a mechanistic insight into the growth promoting properties of alumina (Al2O3) nanoparticles in mouse skin epithelial cells
Swatee Dey et al.
CARCINOGENESIS (2008)
Transcriptional targets of sirtuins in the coordination of mammalian physiology
Jerome N. Feige et al.
CURRENT OPINION IN CELL BIOLOGY (2008)
The Sirtuin family: therapeutic targets to treat diseases of aging
Jill C. Milne et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2008)
Resveratrol inhibits PDGF receptor mitogenic signaling in mesangial cells: role of PTP1B
Balachandar Venkatesan et al.
FASEB JOURNAL (2008)
SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1 - Possible role in AMP-activated protein kinase activation
Fan Lan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
SIRT1 regulates hepatocyte lipid metabolism through activating AMP-activated protein kinase
Xiuyun Hou et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Structure-activity studies on splitomicin derivatives as sirtuin inhibitors and computational prediction of binding mode
Robert C. Neugebauer et al.
JOURNAL OF MEDICINAL CHEMISTRY (2008)
Pulse inhibition of histone deacetylases induces complete resistance to oxidative death in cortical neurons without toxicity and reveals a role for cytoplasmic p21waf1/cip1 in cell cycle-independent neuroprotection
Brett Langley et al.
JOURNAL OF NEUROSCIENCE (2008)
Negative regulation of the deacetylase SIRT1 by DBC1
Wenhui Zhao et al.
NATURE (2008)
DBC1 is a negative regulator of SIRT1
Ja-Eun Kim et al.
NATURE (2008)
Paths of convergence: Sirtuins in aging and neurodegeneration
Li Gan et al.
NEURON (2008)
Resveratrol and novel potent activators of SIRT1: effects on aging and age-related diseases
Mitchell D. Knutson et al.
NUTRITION REVIEWS (2008)
SIRT1 Overexpression Antagonizes Cellular Senescence with Activated ERK/S6k1 Signaling in Human Diploid Fibroblasts
Jing Huang et al.
PLOS ONE (2008)
Histone deacetylase SIRT1 modulates neuronal differentiation by its nuclear translocation
Shin Hisahara et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
SIRT1 inhibition alleviates gene silencing in fragile X mental retardation syndrome
Rea Biacsi et al.
PLOS GENETICS (2008)
A therapeutic role for sirtuins in diseases of aging?
C. H. Westphal et al.
TRENDS IN BIOCHEMICAL SCIENCES (2007)
Bax-inhibiting peptide protects cells from polyglutamine toxicity caused by Ku70 acetylation
Y. Li et al.
CELL DEATH AND DIFFERENTIATION (2007)
Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase
Nidhi Ahuja et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Sirt1 modulates premature senescence-like phenotype in human endothelial cells
Hidetaka Ota et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2007)
Active regulator of SIRT1 cooperates with SIRT1 and facilitates suppression of p53 activity
Eun-Joo Kim et al.
MOLECULAR CELL (2007)
Cytoplasm-localized SIRT1 enhances apoptosis
Qihuang Jin et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2007)
Sirtuins: critical regulators at the crossroads between cancer and aging
L. R. Saunders et al.
ONCOGENE (2007)
SIRT1 activation confers neuroprotection in experimental optic neuritis
Kenneth S. Shindler et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2007)
Sirtuin 2 inhibitors rescue α-synuclein-mediated toxicity in models of Parkinson's disease
Tiago Fleming Outeiro et al.
SCIENCE (2007)
Comparative analysis of the effects of resveratrol in two apoptotic models:: Inhibition of complex I and potassium deprivation in cerebellar neurons
D. Alvira et al.
NEUROSCIENCE (2007)
SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis
Dohoon Kim et al.
EMBO JOURNAL (2007)
Glutathione depletion in hippocampal cells increases levels of H and L ferritin and glutathione S-transferase mRNAs
Nadya Morozova et al.
GENES TO CELLS (2007)
Resveratrol stimulates AMP kinase activity in neurons
Biplab Dasgupta et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Nucleocytoplasmic shuttling of the NAD+-dependent histone deacrtylase SIRT1
Masaya Tanno et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Resveratrol protects dopaminergic neurons in midbrain slice culture from multiple insults
Mitsugi Okawara et al.
BIOCHEMICAL PHARMACOLOGY (2007)
Structural basis for nicotinamide inhibition and base exchange in Sir2 enzymes
Brandi D. Sanders et al.
MOLECULAR CELL (2007)
Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1α
Marie Lagouge et al.
CELL (2006)
A probability-based approach for high-throughput protein phosphorylation analysis and site localization
Sean A. Beausoleil et al.
NATURE BIOTECHNOLOGY (2006)
SirT2 is a histone deacetylase with preference for histone H4 Lys 16 during mitosis
Alejandro Vaquero et al.
GENES & DEVELOPMENT (2006)
Resveratrol - A boon for treating Alzheimer's disease?
Thimmappa S. Anekonda
BRAIN RESEARCH REVIEWS (2006)
Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses
WY Chen et al.
CELL (2005)
Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins
E Michishita et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
Mouse Sir2 homolog SIRT6 is a nuclear ADP-ribosyltransferase
G Liszt et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1α
S Nemoto et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons
JA Parker et al.
NATURE GENETICS (2005)
Mechanism of sirtuin inhibition by nicotinamide:: Altering the NAD+ cosubstrate specificity of a Sir2 enzyme
JL Avalos et al.
MOLECULAR CELL (2005)
Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1
JT Rodgers et al.
NATURE (2005)
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
A Brunet et al.
SCIENCE (2004)
Neuroprotective effects of resveratrol against β-amyloid-induced neurotoxicity in rat hippocampal neurons:: involvement of protein kinase C
YS Han et al.
BRITISH JOURNAL OF PHARMACOLOGY (2004)
Large-scale characterization of HeLa cell nuclear phosphoproteins
SA Beausoleil et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration
T Araki et al.
SCIENCE (2004)
Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ
F Picard et al.
NATURE (2004)
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
KT Howitz et al.
NATURE (2003)
The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase
BJ North et al.
MOLECULAR CELL (2003)
Apoptosis in cerebellar granule neurons is associated with reduced interaction between CREB-binding protein and NF-kappa B
A Yalcin et al.
JOURNAL OF NEUROCHEMISTRY (2003)
Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast Sir2 and human SIRT1
KJ Bitterman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Identification of a class of small molecule inhibitors of the sirtuin family of NAD-dependent deacetylases by phenotypic screening
CM Grozinger et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Negative control of p53 by Sir2α promotes cell survival under stress
JY Luo et al.
CELL (2001)
hSIR2SIRT1 functions as an NAD-dependent p53 deacetylase
H Vaziri et al.
CELL (2001)
NF-κB is involved in the survival of cerebellar granule neurons:: association of Iκβ phosphorylation with cell survival
E Koulich et al.
JOURNAL OF NEUROCHEMISTRY (2001)
Neuroprotective abilities of resveratrol and other red wine constituents against nitric oxide-related toxicity in cultured hippocampal neurons
S Bastianetto et al.
BRITISH JOURNAL OF PHARMACOLOGY (2000)
Resveratrol suppresses TNF-induced activation of nuclear transcription factors NF-κB, activator protein-1, and apoptosis:: Potential role of reactive oxygen intermediates and lipid peroxidation
SK Manna et al.
JOURNAL OF IMMUNOLOGY (2000)