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Jason D. Fontenot et al.
JOURNAL OF IMMUNOLOGY (2017)
Induction of FOXP3 expression in naive human CD4+FOXP3- T cells by T-cell receptor stimulation is transforming growth factor-β-dependent but does not confer a regulatory phenotype
Dat Q. Tran et al.
BLOOD (2007)
CREB/ATF-dependent T cell receptor-induced FoxP3 gene expression:: a role for DNA methylation
Hyoung-Pyo Kim et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
Cyclic adenosine monophosphate is a key component of regulatory T cell mediated suppression
Tobias Bopp et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression
Silvia Deaglio et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
Nonredundant roles for Stat5a/b in directly regulating Foxp3
Zhengju Yao et al.
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Cutting edge:: IL-2 is essential for TGF-β-mediated induction of Foxp3+ T regulatory cells
Todd S. Davidson et al.
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Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production
Sarah E. Allan et al.
INTERNATIONAL IMMUNOLOGY (2007)
Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity
Jun Yamanouchi et al.
NATURE GENETICS (2007)
Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression
Yisong Y. Wan et al.
NATURE (2007)
Helper T cell IL-2 production is limited by negative feedback and STAT-dependent cytokine signals
Alejandro V. Villarino et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
IL-2 receptor β-dependent STAT5 activation is required for the development of Foxp3+ regulatory T cells
Matthew A. Burchill et al.
JOURNAL OF IMMUNOLOGY (2007)
Transient expression of FOXP3 in human activated nonregulatory CD4(+) T cells
Jun Wang et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2007)
IL-2 and IL-15 each mediate de novo induction of FOXP3 expression in human tumor antigen-specific CD8 T cells
Mojgan Ahmadzadeh et al.
JOURNAL OF IMMUNOTHERAPY (2007)
IL-2 regulates FOXP3 expression in human CD4+CD25+ regulatory T cells through a STAT-dependent mechanism and induces the expansion of these cells in vivo
Emmanuel Zorn et al.
BLOOD (2006)
FOXP3 controls regulatory T cell function through cooperation with NFAT
Yongqing Wu et al.
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MA Gavin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Foxp3 represses retroviral transcription by targeting both NF-κB and CREB pathways
Christian Grant et al.
PLOS PATHOGENS (2006)
Molecular mechanisms underlying FOXP3 induction in human T cells
Pierre-Yves Mantel et al.
JOURNAL OF IMMUNOLOGY (2006)
Inducing and expanding regulatory T cell populations by foreign antigen
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Foxp3 interacts with nuclear factor of activated T cells and NF-κB to repress cytokine gene expression and effector functions of T helper cells
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Expression of FOXP3 mRNA is not confined to CD4(+)CD25(+) T regulatory cells in humans
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JOURNAL OF EXPERIMENTAL MEDICINE (2004)
Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-β induction of transcription factor Foxp3
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JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Stat5 synergizes with T cell receptor/antigen stimulation in the development of lymphoblastic lymphoma
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JOURNAL OF EXPERIMENTAL MEDICINE (2003)
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NATURE MEDICINE (2003)
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NATURE IMMUNOLOGY (2003)
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
JD Fontenot et al.
NATURE IMMUNOLOGY (2003)
Control of regulatory T cell development by the transcription factor Foxp3
S Hori et al.
SCIENCE (2003)
The amount of scurfin protein determines peripheral T cell number and responsiveness
R Khattri et al.
JOURNAL OF IMMUNOLOGY (2001)
Scurfin (FOXP3) acts as a repressor of transcription and regulates T cell activation
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JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy
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NATURE GENETICS (2001)
Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
ME Brunkow et al.
NATURE GENETICS (2001)
The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
CL Bennett et al.
NATURE GENETICS (2001)
JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome
TA Chatila et al.
JOURNAL OF CLINICAL INVESTIGATION (2000)
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