期刊
PLANTA MEDICA
卷 85, 期 2, 页码 154-159出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/a-0733-7229
关键词
Actaea heracleifolia; Ranunculaceae; 15; 16-seco-cycloartane triterpene; cycloartane triterpene glycosides; cytotoxicity; NMR
资金
- Autonomous Deployment Project of Kunming Institute of Botany, CAS [KIB2017010]
- Program for National Natural Science Foundation of China [U1132604, 81302670]
- Major Program of CAS [KSZD-EW-Z-004-01]
One new 15,16-seco-cycloartane triterpene (1), three new cycloartane triterpene glycosides (2-4), and five known compounds (5-9) were isolated from the aerial parts of Actaea heracleifolia. The chemical structures of these compounds were determined on the basis of NMR analysis, HRTOF-ESIMS data, and other spectroscopic methods. Selected compounds were evaluated for their cytotoxicity against human tumor cell lines (HL-60, SMMC-7721, A549, MCF-7, and SW480) in vitro. Compounds 3 and 4 showed weak activity against the HL-60, A-549, and MCF-7 cell lines with IC50 values ranging from 21.34 to 36.98 mu M.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据