期刊
PLANTA MEDICA
卷 78, 期 17, 页码 1857-1860出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0032-1315386
关键词
Ormocarpum trichocarpum; Papilionaceae; antiplasmodial activity; antibacterial activity; biflavanone; biscoumarin
资金
- National Research Foundation, Pretoria
- University of KwaZulu-Natal
Using activity-guided fractionation based on in vitro antibacterial assays, five biflavonoids, among them two new ones, were isolated from the aerial parts of Ormocarpum trichocarpum. The isolated compounds showed MIC values in the range of 4.0 to 136.7 mu M against Staphylococcus aureus, Bacillus subtilis, Escherichia coli, and Klebsiella pneumonia and IC50 values in the range of 4.30 to 94.32 mu M against the chloroquine-sensitive D10 Plasmodium falciparum strain.
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