4.5 Article

Triterpenes and Triterpenoid Saponins from the Leaves of Ilex kudincha

期刊

PLANTA MEDICA
卷 77, 期 16, 页码 1835-1840

出版社

GEORG THIEME VERLAG KG
DOI: 10.1055/s-0030-1271164

关键词

Ilex kudincha; Aquifoliaceae; triterpenoids; kudinchalactone A; ilekudinchosides A-D; antibacterial activity

资金

  1. National Key Technologies R & D Program of China [2009ZX09501-011]
  2. National Major Special Science and Technology Project [2010ZX09401-304-104A]

向作者/读者索取更多资源

One new triterpene, kudinchalactone A (1), and four new triterpenoid saponins, ilekudinchosides A-D (2-5), were isolated from the leaves of Ilex kudincha C.J. Tseng along with eight known triterpenoids. These new compounds were elucidated by spectroscopic methods including 1D and 2D NMR, HR-TOF-MS, and CD spectra. Compounds 2, 3, 12, and 13 showed antibacterial activities against Staphylococcus aureus (SA) and methicillin-resistant Staphylococcus aureus (MRSA).

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