期刊
PLANT PHYSIOLOGY
卷 152, 期 1, 页码 217-225出版社
AMER SOC PLANT BIOLOGISTS
DOI: 10.1104/pp.109.145532
关键词
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资金
- National Institutes of Health [GM 36397-22]
- U.S. Department of Energy's Office of Biological and Environmental Research [DEG0796ER20257]
- Environmental Remediation Sciences Division [DEFG0203ER63620]
- U.S. Department of Agriculture
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM036397] Funding Source: NIH RePORTER
Phosphate (Pi) availability is a major constraint to plant growth. Consequently, plants have evolved complex adaptations to tolerate low Pi conditions. Numerous genes implicated in these adaptations have been identified, but their chromatin-level regulation has not been investigated. The nuclear actin-related protein ARP6 is conserved among all eukaryotes and is an essential component of the SWR1 chromatin remodeling complex, which regulates transcription via deposition of the H2A.Z histone variant into chromatin. Here, we demonstrate that ARP6 is required for proper H2A.Z deposition at a number of Pi starvation response (PSR) genes in Arabidopsis (Arabidopsis thaliana). The loss of H2A.Z at these target loci results in their derepression in arp6 mutants and correlates with the presence of multiple Pi-starvation-related phenotypes, including shortened primary roots and increases in the number and length of root hairs, as well as increased starch accumulation and phosphatase activity in shoots. Our data suggest a model for chromatin-level control of Pi starvation responses in which ARP6-dependent H2A.Z deposition modulates the transcription of a suite of PSR genes.
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