期刊
PLANT BIOTECHNOLOGY JOURNAL
卷 8, 期 9, 页码 939-953出版社
WILEY
DOI: 10.1111/j.1467-7652.2010.00559.x
关键词
cereal; seed storage protein; transcription; protein sorting; processing; transgenic plant industry
资金
- Ministry of Agriculture, Forest and Fishery of Japan [GMC0003]
- Ministry of Economy, Trade and Industry
- Ministry of Education, Culture, Sports, Science and Technology of Japan [19780011, 22688001]
- Grants-in-Aid for Scientific Research [19780011, 22688001] Funding Source: KAKEN
Cereal seeds provide an ideal production platform for high-value products such as pharmaceuticals and industrial materials because seeds have ample and stable space for the deposition of recombinant products without loss of activity at room. Seed storage proteins (SSPs) are predominantly synthesized and stably accumulated in maturing endosperm tissue. Therefore, understanding the molecular mechanisms regulating SSP expression and accumulation is expected to provide valuable information for producing higher amounts of recombinant products. SSP levels are regulated by several steps at the transcriptional (promoters, transcription factors), translational and post-translational levels (modification, processing trafficking, and deposition). Our objective is to develop a seed production platform capable of producing very high yields of recombinant product. Towards this goal, we review here the individual regulatory steps controlling SSP synthesis and accumulation.
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