期刊
PHYTOTHERAPY RESEARCH
卷 26, 期 4, 页码 617-619出版社
WILEY-BLACKWELL
DOI: 10.1002/ptr.3589
关键词
Aloe vera; antipsoriatic?activity; orthokeratosis; morphometric; mouse tail model
资金
- Tamilnadu Science and Technology, Chennai, India
Aloe vera gel is used traditionally for the treatment of skin diseases, including psoriasis. An ethanolic extract of the gel was assessed for antipsoriatic activity using a mouse tail model of psoriasis. The extract produced a significant differentiation in the epidermis, as seen from its degree of orthokeratosis (85.07 +/- 3.36%) when compared with the negative control (17.30 +/- 4.09%). This was equivalent to the effect of the standard positive control, tazarotene (0.1%) gel, which showed a 90.03 +/- 2.00% degree of orthokeratosis. The ethanolic extract of Aloe vera leaf gel also produced a significant increase in relative epidermal thickness when compared with the control group, whereas the standard tazarotene showed no change. Taken together, the extract showed an overall antipsoriatic activity of 81.95%, compared with 87.94 for tazarotene, in the mouse tail model for psoriasis. Copyright (C) 2011 John Wiley & Sons, Ltd.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据