期刊
PHYTOCHEMISTRY LETTERS
卷 10, 期 -, 页码 55-59出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.phytol.2014.08.001
关键词
Gardneria multiflora; 7S-oxindole alkaloids; Structure elucidation; Cytotoxicity
资金
- National Natural Science Foundation of China [21172225, 31370377]
- Young Academic and Technical Leader Raising Foundation of Yunnan Province [2010CI049]
- XiBuZhiGuang Project of Chinese Academy of Sciences
Seven new oxindole alkaloids, gardmutines A-F (1-6) and 18-hydroxy-chitosenine (7), along with 15 known alkaloids, were isolated from the aerial parts of Gardneria multiflora Makino. The structures of the alkaloids were established by spectroscopic methods. Alkaloids 1-6 are the first Gardneria alkaloids possessing a 7S configuration. Gardmutines D and E were cytotoxic to HeLa, MCF-7 breast, and SW-480 colon cancer cell lines. (C) 2014 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
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