期刊
PHYTOCHEMISTRY LETTERS
卷 6, 期 3, 页码 318-321出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.phytol.2013.03.012
关键词
Endophytic fungus; Liverwort; Metabolites; Immunosuppressive activity
资金
- National Natural Science Foundation of China [30925038]
Three new xanthone derivatives, including two first reported containing sulfur as natural products: sydoxanthone A (1) and sydoxanthone B (2), and 13-O-acetylsydowinin B (3) were isolated from an endophytic fungus Aspergillus sydowii, occurring in the livewort Scapania ciliata S. Lac, together with seven known biosynthetically related compounds (4-10). Their structures were established primarily by NMR, UV and MS data. In vitro suppression test on the Con A- and LPS-induced proliferations of mouse splenic lymphocytes showed that compounds 7 and 8 displayed moderate immunosuppressive activities. (C) 2013 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
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