期刊
PHYTOCHEMISTRY
卷 107, 期 -, 页码 182-189出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.phytochem.2014.08.003
关键词
Tribulus terrestris; Liliaceae; Steroidal saponins; Terrestrinins C-I; Platelet aggregation
资金
- Municipal Natural Science Foundation of Beijing [7090001]
- National Natural Science Foundation of China Union Foundation of Yunnan Province [U10132601]
Sixteen steroidal saponins, including seven previously unreported compounds, were isolated from Tribulus terrestris. The structures of the saponins were established using 1D and 2D NMR spectroscopy, mass spectrometry, and chemical methods. They were identified as: 26-O-beta-D-glucopyranosyl-(25R)-furost-4-en-2 alpha,3 beta,22 alpha,26-tetrol-12-one (terrestrinin C), 26-O-beta-D-glucopyranosyl-(25R)-furost-4-en-22 alpha,26-diol-3,12-dione (terrestrinin D), 26-O-beta-D-glucopyranosyl-(25S)-furost-4-en-22 alpha,26-diol-3,6,12-trione (terrestrinin E), 26-O-beta-D-glucopyranosyl-(25R)-5 alpha-furostan-3 beta,22 alpha,26-triol-12-one (terrestrinin F), 26-O-beta-D-glucopyranosyl-(25R)-furost-4-en-12 beta,22 alpha,26-triol-3-one (terrestrinin G), 26-O-beta-D-glucopyranosyl-(1 -> 6)-beta-D-glucopyranosyl-(25R)-furost-4-en-22 alpha,26-diol-3,12-dione (terrestrinin H), and 24-O-beta-D-glucopyranosyl-(25S)-5 alpha-spirostan-3 beta,24 beta-diol-12-one-3-O-beta-D-glucopyranosyl-(1 -> 4)-beta-D-galactopyranoside (terrestrinin I). The isolated compounds were evaluated for their platelet aggregation activities. Three of the known saponins exhibited strong effects on the induction of platelet aggregation. (C) 2014 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据