期刊
PHYTOCHEMISTRY
卷 73, 期 -, 页码 119-126出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.phytochem.2011.09.011
关键词
Astragalus stereocalyx; Cycloartane saponins; Cycloasgenin C
Six cycloartane-type triterpene glycosides were isolated from Astragalus stereocalyx along with six known cycloartane-type glycosides. Their structures were established by the extensive use of 1D and 2D-NMR experiments along with ESIMS and HRMS analysis. Three compounds are based on an aglycon characterized by the occurrence of an unusual hydroxyl group at position 20, whereas three other compounds are based on cycloasgenin C as aglycon, so far reported from Astragalus spp. All the compounds were tested for their cytotoxic activity against a number of cancer cell lines. One compound exhibited activity versus human cervical cancer (Hela) with an IC50 value 10 mu M. (C) 2011 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据