Phenolic compounds and rare polyhydroxylated triterpenoid saponins from Eryngium yuccifolium

Phytochemical investigation on the whole plant of Eryngium yuccifolium resulted in the isolation and identification of three phenolic compounds (1-3) and 12 polyhydroxylated triterpenoid saponins, named eryngiosides A-L (4-15), together with four known compounds kaempferol-3-O-(2,6-di-O-trans-p-coumaroyl)-beta-D-glucopyranoside (16), caffeic acid (17), 21 beta-angeloyloxy-3 beta-[beta-D-glucopyranosyl-(1-2)1[beta-D-xylopyranosyl-(1 -> 3)]-beta-D-glucuronopyranosyloxyolean-12-ene-15 alpha,16 alpha,22 alpha,28-tetrol (18), and saniculasaponin III (19). This study reports the isolation of these compounds and their structural elucidation by extensive spectroscopic analyses and chemical degradation. (C) 2008 Elsevier Ltd. All rights reserved.