期刊
PHYSIOLOGY
卷 25, 期 4, 页码 230-238出版社
AMER PHYSIOLOGICAL SOC
DOI: 10.1152/physiol.00007.2010
关键词
-
类别
资金
- Swedish Research Council, Soderberg Foundation
- European Commission [Health-F2-2007-201144]
- Karolinska Institutet
Cannabinoid receptors and endocannabinoid signaling are distributed throughout the rostrocaudal neuraxis. Retrograde signaling via endocannabinoid mediates synaptic plasticity in many regions in the central nervous system. Here, we review the role of endocannabinoid signaling in different parts of the vertebrate motor system from networks responsible for the execution of movement to planning centers in the basal ganglia and cortex. The ubiquity of endocannabinoid-mediated plasticity suggests that it plays an important role in producing motion from defined circuitries and also for reconfiguring networks to learn new motor skills. The long-term plasticity induced by endocannabinoids may provide a long-term buffer that stabilizes the organization of motor circuits and their activity.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据