期刊
PHYSIOLOGY
卷 24, 期 2, 页码 107-116出版社
AMER PHYSIOLOGICAL SOC
DOI: 10.1152/physiol.00038.2008
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类别
资金
- National Institutes of Health
- American Diabetes Association
- Heart and Stroke Foundation of Ontario
- Canadian Institutes of Health Research
Through oxygen-dependent release of the vasodilator ATP, the mobile erythrocyte plays a fundamental role in matching microvascular oxygen supply with local tissue oxygen demand. Signal transduction within the erythrocyte and microvessels as well as feedback mechanisms controlling ATP release have been described. Our understanding of the impact of this novel control mechanism will rely on the integration of in vivo experiments and computational models.
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