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JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Recognition of polyubiquitin isoforms by the multiple ubiquitin binding modules of isopeptidase T
Francisca E. Reyes-Turcu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Hydrogen peroxide prolongs nuclear localization of NF-κB in activated cells by suppressing negative regulatory mechanisms
Karine Enesa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Targeted inactivation of the COP9 signalosome impairs multiple stages of T cell development
Martina Panattoni et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
Molecular basis for the unique deubiquitinating activity of the NF-κB inhibitor A20
Su-Chang Lin et al.
JOURNAL OF MOLECULAR BIOLOGY (2008)
Quantitative analysis of global ubiquitination in HeLa cells by mass spectrometry
David Meierhofer et al.
JOURNAL OF PROTEOME RESEARCH (2008)
Dissection of the carboxyl-terminal domain of the proteasomal subunit Rpn11 in maintenance of mitochondrial structure and function
Teresa Rinaldi et al.
MOLECULAR BIOLOGY OF THE CELL (2008)
Regulation of mitochondrial morphology by USP30, a deubiquitinating enzyme present in the mitochondrial outer membrane
Nobuhiro Nakamura et al.
MOLECULAR BIOLOGY OF THE CELL (2008)
Relative structural and functional roles of multiple deubiquitylating proteins associated with mammalian 26S proteasome
Elena Koulich et al.
MOLECULAR BIOLOGY OF THE CELL (2008)
Mechanism and consequences for paralog-specific sumoylation of ubiquitin-specific protease 25
Erik Meulmeester et al.
MOLECULAR CELL (2008)
Distinct modes of regulation of the Uch37 deubiquitinating enzyme in the proteasome and in the Ino80 chromatin-remodeling complex
Tingting Yao et al.
MOLECULAR CELL (2008)
The structure of the CYLD USP domain explains its specificity for Lys63-linked polyubiquitin and reveals a B box module
David Komander et al.
MOLECULAR CELL (2008)
Structural basis for specific cleavage of Lys 63-linked polyubiquitin chains
Yusuke Sato et al.
NATURE (2008)
The deubiquitinylation and localization of PTEN are regulated by a HAUSP-PML network
Min Sup Song et al.
NATURE (2008)
Zinc-finger UBPs: regulators of deubiquitylation
Jacques Bonnet et al.
TRENDS IN BIOCHEMICAL SCIENCES (2008)
Vasopressin-inducible ubiquitin-specific protease 10 increases ENaC cell surface expression by deubiquitylating and stabilizing sorting nexin 3
Sheerazed Boulkroun et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2008)
A UAF1-containing multisubunit protein complex regulates the Fanconi anemia pathway
Martin A. Cohn et al.
MOLECULAR CELL (2007)
The age of crosstalk: Phosphorylation, ubiquitination, and beyond
Tony Hunter
MOLECULAR CELL (2007)
DUBA: A deubiquitinase that regulates type I interferon production
Nobuhiko Kayagaki et al.
SCIENCE (2007)
Human USP3 is a chromatin modifier required for S phase progression and genome stability
Francesco Nicassio et al.
CURRENT BIOLOGY (2007)
Inactivation of the mouse Atxn3 (ataxin-3) gene increases protein ubiquitination
Ina Schmitt et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Regulation of cell cycle progression and gene expression by H2A deubiquitination
Heui-Yun Joo et al.
NATURE (2007)
The MIT domain of UBPY constitutes a CHMP binding and endosomal localization signal required for efficient epidermal growth factor receptor degradation
Paula E. Row et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
14-3-3-dependent inhibition of the deubiquitinating activity of UBPY and its cancellation in the M phase
Emi Mizuno et al.
EXPERIMENTAL CELL RESEARCH (2007)
A histone H2A deubiquitinase complex coordinating histone acetylation and H1 dissociation in transcriptional regulation
Ping Zhu et al.
MOLECULAR CELL (2007)
Biochemical characterization of USP7 reveals post-translational modification sites and structural requirements for substrate processing and subcellular localization
Amaury Fernandez-Montalvan et al.
FEBS JOURNAL (2007)
Solution structure of the Ubp-M BUZ domain, a highly specific protein module that recognizes the C-terminal tail of free ubiquitin
Ming-Tao Pai et al.
JOURNAL OF MOLECULAR BIOLOGY (2007)
Differential redox regulation within the PTP superfamily
Sarah H. Ross et al.
CELLULAR SIGNALLING (2007)
Essential role of ubiquitin-specific protease 8 for receptor tyrosine kinase stability and endocytic trafficking in vivo
Sandra Niendorf et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
A ubiquitin stress response induces altered proteasome composition
John Hanna et al.
CELL (2007)
The emerging shape of the ESCRT machinery
Roger L. Williams et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Functional genomics and biochemical characterization of the C-elegans orthologue of the Machado-Joseph disease protein ataxin-3
Ana-Joao Rodrigues et al.
FASEB JOURNAL (2007)
Early aldosterone-induced gene product regulates the epithelial sodium channel by deubiquitylation
Panagiotis Fakitsas et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2007)
CSN controls NF-κB by deubiquitinylation of IκBα
Katrin Schweitzer et al.
EMBO JOURNAL (2007)
Decoding ubiquitin sorting signals for clathrin-dependent endocytosis by CLASPs
Linton M. Traub et al.
JOURNAL OF CELL SCIENCE (2007)
Oncomine 3.0: Genes, pathways, and networks in a collection of 18,000 cancer gene expression profiles
Daniel R. Rhodes et al.
NEOPLASIA (2007)
Dopaminergic neuronal loss in transgenic mice expressing the Parkinson's disease-associated UCH-L1 193M mutant
Rieko Setsuie et al.
NEUROCHEMISTRY INTERNATIONAL (2007)
hRpn13/ADRM1/GP110 is a novel proteasome subunit that binds the deubiquitinating enzyme, UCH37
Xiao-Bo Qiu et al.
EMBO JOURNAL (2006)
Transgenic rescue of ataxia mice with neuronal-specific expression of ubiquitin-specific protease 14
Stephen Crimmins et al.
JOURNAL OF NEUROSCIENCE (2006)
Endocytosis:: the DUB version
Michael J. Clague et al.
TRENDS IN CELL BIOLOGY (2006)
Deubiquitinating enzyme Ubp6 functions noncatalytically to delay proteasomal degradation
John Hanna et al.
CELL (2006)
FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP
Armando van der Horst et al.
NATURE CELL BIOLOGY (2006)
Proteasome recruitment and activation of the Uch37 deubiquitinating enzyme by Adrm1
Tingting Yao et al.
NATURE CELL BIOLOGY (2006)
A systematic analysis of human CHMP protein interactions: Additional MIT domain-containing proteins bind to multiple components of the human ESCRT III complex
Hilda T. H. Tsang et al.
GENOMICS (2006)
Ubiquitin hydrolase Uch-L1 rescues β-amyloid-induced decreases in synaptic function and contextual memory
Bing Gong et al.
CELL (2006)
Interaction of AMSH with ESCRT-III and deubiquitination of endosomal cargo
Monica Agromayor et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
A deubiquitinating enzyme UBPY regulates the level of protein ubiquitination on endosomes
Emi Mizuno et al.
TRAFFIC (2006)
The ubiquitin isopeptidase UBPY regulates endosomal ubiquitin dynamics and is essential for receptor down-regulation
PE Row et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Regulation of monoubiquitinated PCNA by DUB autocleavage
TT Huang et al.
NATURE CELL BIOLOGY (2006)
The ubiquitin binding domain ZnFUBP recognizes the C-terminal diglycine motif of unanchored ubiquitin
FE Reyes-Turcu et al.
CELL (2006)
Structural basis for conformational plasticity of the Parkinson's disease-associated ubiquitin hydrolase UCH-L1
C Das et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Degradation of endocytosed epidermal growth factor and virally ubiquitinated major histocompatibility complex class I is independent of mammalian ESCRTII
K Bowers et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Activation of the endosome-associated ubiquitin isopeptidase AMSH by STAM, a component of the multivesicular body-sorting machinery
J McCullough et al.
CURRENT BIOLOGY (2006)
The region-specific functions of two ubiquitin C-terminal hydrolase isozymes along the epididymis
J Kwon et al.
EXPERIMENTAL ANIMALS (2006)
A genomic and functional inventory of deubiquitinating enzymes
SMB Nijman et al.
CELL (2005)
The deubiquitinating enzyme UCH37 interacts with Smads and regulates TGF-β signalling
SJ Wicks et al.
ONCOGENE (2005)
Loss of Usp14 results in reduced levels of ubiquitin in ataxia mice
C Anderson et al.
JOURNAL OF NEUROCHEMISTRY (2005)
The pairwise energy content estimated from amino acid composition discriminates between folded and intrinsically unstructured proteins
Z Dosztányi et al.
JOURNAL OF MOLECULAR BIOLOGY (2005)
Protein homology detection by HMM-HMM comparison
J Söding
BIOINFORMATICS (2005)
The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway
SMB Nijman et al.
MOLECULAR CELL (2005)
Structure of the ubiquitin hydrolase UCH-L3 complexed with a suicide substrate
S Misaghi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
UCHL1 is a Parkinson's disease susceptibility gene
DM Maraganore et al.
ANNALS OF NEUROLOGY (2004)
Oxidative modifications and down-regulation of ubiquitin carboxyl-terminal hydrolase L1 associated with idiopathic Parkinson's and Alzheimer's diseases
J Choi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
A dynamic role of HAUSP in the p53-Mdm2 pathway
MY Li et al.
MOLECULAR CELL (2004)
AMSH is an endosome-associated ubiquitin isopeptidase
J McCullough et al.
JOURNAL OF CELL BIOLOGY (2004)
De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-κB signalling
IE Wertz et al.
NATURE (2004)
Developmental regulation of ubiquitin C-terminal hydrolase isozyme expression during spermatogenesis in mice
J Kwon et al.
BIOLOGY OF REPRODUCTION (2004)
Mechanism and function of deubiquitinating enzymes
AY Amerik et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2004)
JAMM: A metalloprotease-like zinc site in the proteasome and signalosome
XI Ambroggio et al.
PLOS BIOLOGY (2004)
Fat facets and liquid facets promote Delta endocytosis and Delta signaling in the signaling cells
E Overstreet et al.
DEVELOPMENT (2004)
The polyglutamine neurodegenerative protein ataxin-3 binds polyubiquitylated proteins and has ubiquitin protease activity
B Burnett et al.
HUMAN MOLECULAR GENETICS (2003)
Ubiquitination regulates PSD-95 degradation and AMPA receptor surface expression
M Colledge et al.
NEURON (2003)
Gene expression profiling in ataxin-3 expressing cell lines reveals distinct effects of normal and mutant ataxin-3
BO Evert et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2003)
COP9 signalosome: A multifunctional regulator of SCF and other cullin-based ubiquitin Ligases
GA Cope et al.
CELL (2003)
Ubiquitin carboxy-terminal hydrolase L1 binds to and stabilizes monoubiquitin in neuron
H Osaka et al.
HUMAN MOLECULAR GENETICS (2003)
A proteomics approach to understanding protein ubiquitination
JM Peng et al.
NATURE BIOTECHNOLOGY (2003)
A novel type of deubiquitinating enzyme*
PC Evans et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Otubains: a new family of cysteine proteases in the ubiquitin pathway
MY Balakirev et al.
EMBO REPORTS (2003)
Elucidation of ataxin-3 and ataxin-7 function by integrative bioinformatics
H Scheel et al.
HUMAN MOLECULAR GENETICS (2003)
Structural properties of polyubiquitin chains in solution
R Varadan et al.
JOURNAL OF MOLECULAR BIOLOGY (2002)
Synaptic defects in ataxia mice result from a mutation in Usp14, encoding a ubiquitin-specific protease
SM Wilson et al.
NATURE GENETICS (2002)
Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1
GA Cope et al.
SCIENCE (2002)
Role of Rpn11 metalloprotease in deubiquitination and degradation by the 26S proteasome
R Verma et al.
SCIENCE (2002)
A cryptic protease couples deubiquitination and degradation by the proteasome
TT Yao et al.
NATURE (2002)
Dysregulation of protein modification by ISG15 results in brain cell injury
KJ Ritchie et al.
GENES & DEVELOPMENT (2002)
Multiple associated proteins regulate proteasome structure and function
DS Leggett et al.
MOLECULAR CELL (2002)
Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization
MY Li et al.
NATURE (2002)
UBP43 (USP18) specifically removes ISG15 from conjugated proteins
MP Malakhov et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Loss of neurons in the hippocampus and cerebral cortex of AMSH-deficient mice
N Ishii et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
A novel active site-directed probe specific for deubiquitylating enzymes reveals proteasome association of USP14
A Borodovsky et al.
EMBO JOURNAL (2001)
A deubiquitinating enzyme UBPY interacts with the Src homology 3 domain of Hrs-binding protein via a novel binding motif PX(V/I)(D/N)RXXKP
M Kato et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
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