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Regulatory phosphorylation sites in the NH2 terminus of the renal Na-K-Cl cotransporter (NKCC2)
I Giménez et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2005)
Moderate-to-severe ischemic conditions increase activity and phosphorylation of the cerebral microvascular endothelial cell Na+-K+-Cl- cotransporter
S Foroutan et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2005)
NKCC1 transporter facilitates seizures in the developing brain
VI Dzhala et al.
NATURE MEDICINE (2005)
Apoptosis-associated tyrosine kinase (AATYK) has differential Ca2+-dependent phosphorylation states in response to survival and apoptotic conditions in cerebellar granule cells
M Tomomura et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases
AC Vitari et al.
BIOCHEMICAL JOURNAL (2005)
Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein
OM Andersen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Arginine vasopressin stimulation of cerebral microvascular endothelial cell Na-K-Cl cotransporter activity is V1 receptor and [Ca] dependent
ME O'Donnell et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2005)
Role for protein phosphatase 2A in the regulation of Calu-3 epithelial Na+-K+-2Cl-, type 1 co-transport function
CM Liedtke et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Scooby-domain: prediction of globular domains in protein sequence
RA George et al.
NUCLEIC ACIDS RESEARCH (2005)
Relative contribution of chloride channels and transporters to regulatory volume decrease in human glioma cells
NJ Ernest et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2005)
Molecular physiology and pathophysiology of electroneutral cation-chloride cotransporters
G Gamba
PHYSIOLOGICAL REVIEWS (2005)
Hypotonic shock mediation by p38 MAPK, JNK, PKC, FAK, OSR1 and SPAK in osmosensing chloride secreting cells of killifish opercular epithelium
WS Marshall et al.
JOURNAL OF EXPERIMENTAL BIOLOGY (2005)
Mechanism of the excitatory Cl- response in mouse olfactory receptor neurons
J Reisert et al.
NEURON (2005)
GCK-3, a newly identified Ste20 kinase, binds to and regulates the activity of a cell cycle-dependent CIC anion channel
J Denton et al.
JOURNAL OF GENERAL PHYSIOLOGY (2005)
Linkage and association of the mitochondrial aspartate/ glutamate carrier SLC25A12 gene with autism
N Ramoz et al.
AMERICAN JOURNAL OF PSYCHIATRY (2004)
Characterization of OSR1, a member of the mammalian Ste20p/germinal center kinase subfamily
W Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
SPAK kinase is a substrate and target of PKCθ in T-cell receptor-induced AP-1 activation pathway
YQ Li et al.
EMBO JOURNAL (2004)
LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1
JM Lizcano et al.
EMBO JOURNAL (2004)
WNK4 regulates apical and basolateral Cl- flux in extrarenal epithelia
KT Kahle et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Ion channels and amino acid transporters support the growth and invasion of primary brain tumors
H Sontheimer
MOLECULAR NEUROBIOLOGY (2004)
Regulation of K-Cl cotransport: from function to genes
NC Adragna et al.
JOURNAL OF MEMBRANE BIOLOGY (2004)
Chloride accumulation in mammalian olfactory sensory neurons
H Kaneko et al.
JOURNAL OF NEUROSCIENCE (2004)
Bumetanide inhibition of the blood-brain barrier Na-L-Cl cotransporter reduces edema formation in the rat middle cerebral artery occlusion model of stroke
ME O'Donnell et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2004)
Analysis of the LKB1-STRAD-MO25 complex
J Boudeau et al.
JOURNAL OF CELL SCIENCE (2004)
The Traf2- and Nck-interacting kinase as a putative effector of Rap2 to regulate actin cytoskeleton
K Taira et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Cloning, genomic organization, alternative splicing and expression analysis of the human gene RWK3 (PRKWNK3)
S Holden et al.
GENE (2004)
Duplication and divergence: The evolution of new genes and old ideas
JS Taylor et al.
ANNUAL REVIEW OF GENETICS (2004)
Crystal structure of the TAO2 kinase domain: Activation and specificity of a Ste20p MAP3K
TJ Zhou et al.
STRUCTURE (2004)
Hsp105α suppresses Hsc70 chaperone activity by inhibiting Hsc70 ATPase activity
N Yamagishi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Characterization of the interaction of the stress kinase SPAK with the Na+-K+-2Cl- cotransporter in the nervous system -: Evidence for a scaffolding role of the kinase
K Piechotta et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Multiple promoters in the WNK1 gene: One controls expression of a kidney-specific kinase-defective isoform
C Delaloy et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Apoptosis-associated tyrosine kinase is a Cdk5 activator p35 binding protein
N Honma et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
Loss of K-Cl co-transporter KCC3 causes deafness, neurodegeneration and reduced seizure threshold
T Boettger et al.
EMBO JOURNAL (2003)
KCl cotransport is an important modulator of human cervical cancer growth and invasion
MR Shen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
MO25α/β interact with STRADα/β enhancing their ability to bind, activate and localize LKB1 in the cytoplasm
J Boudeau et al.
EMBO JOURNAL (2003)
WNK1, a gene within a novel blood pressure control pathway, tissue-specifically generates radically different isoforms with and without a kinase domain
M O'Reilly et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2003)
Comparative studies of a new subfamily of human Ste20-like kinases: homodimerization, subcellular localization, and selective activation of MKK3 and p38
JT Yustein et al.
ONCOGENE (2003)
Trans-synaptic shift in anion gradient in spinal lamina I neurons as a mechanism of neuropathic pain
JAM Coull et al.
NATURE (2003)
PASK (proline-alanine-rich STE20-related kinase), a regulatory kinase of the Na-K-Cl cotransporter (NKCC1)
BFX Dowd et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Evolution by gene duplication: an update
JZ Zhang
TRENDS IN ECOLOGY & EVOLUTION (2003)
The prostate-derived sterile 20-like kinase (PSK) regulates microtubule organization and stability
C Mitsopoulos et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Stk10, a new member of the polo-like kinase kinase family highly expressed in hematopoietic tissue
SA Walter et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Differential expression and function of apoptosis-associated tyrosine kinase (AATYK) in the developing mouse brain
M Tomomura et al.
MOLECULAR BRAIN RESEARCH (2003)
Myo3A, one of two class III myosin genes expressed in vertebrate retina, is localized to the calycal processes of rod and cone photoreceptors and is expressed in the sacculus
AC Dosé et al.
MOLECULAR BIOLOGY OF THE CELL (2003)
Stability of actin cytoskeleton and PKC-δ binding to actin regulate NKCC1 function in airway epithelial cells
CM Liedtke et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2003)
Activation of human CD4+ cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype
C Kemper et al.
NATURE (2003)
A role for Drosophila LKB1 in anterior-posterior axis formation and epithelial polarity
SG Martin et al.
NATURE (2003)
Non-syndromic recessive auditory neuropathy is the result of mutations in the otoferlin (OTOF) gene
R Varga et al.
JOURNAL OF MEDICAL GENETICS (2003)
Cation chloride cotransporters interact with the stress-related kinases Ste20-kelated proline-alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1)
K Piechotta et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Regulation of WNK1 by an autoinhibitory domain and autophosphorylation
BE Xu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
GA Calin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Decreased blood pressure and vascular smooth muscle tone in mice lacking basolateral Na+-K+-2Cl- cotransporter
JW Meyer et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2002)
The K-Cl cotransporter KCC3 is mutant in a severe peripheral neuropathy associated with agenesis of the corpus callosum
HC Howard et al.
NATURE GENETICS (2002)
Evolution of protein kinase signaling from yeast to man
G Manning et al.
TRENDS IN BIOCHEMICAL SCIENCES (2002)
Excitatory actions of GABA during development: The nature of the nurture
Y Ben-Ari
NATURE REVIEWS NEUROSCIENCE (2002)
Cell cycle- and swelling-induced activation of a Caenorhabditis elegans ClC channel is mediated by CeGLC-7α/β phosphatases
E Rutledge et al.
JOURNAL OF CELL BIOLOGY (2002)
Q829X, a novel mutation in the gene encoding otoferlin (OTOF), is frequently found in Spanish patients with prelingual non-syndromic hearing loss
V Migliosi et al.
JOURNAL OF MEDICAL GENETICS (2002)
From flies' eyes to our ears: Mutations in a human class III myosin cause progressive nonsyndromic hearing loss DFNB30
T Walsh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Expression and regulation of the Na+/K+/2Cl- cotransporter NKCC1 in rat liver and human HuH-7 hepatoma cells
F Schliess et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2002)
Cdc42 regulation of kinase activity and signaling by the yeast p21-activated kinase Ste20
RE Lamson et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
SnapDRAGON: a method to delineate protein structural domains from sequence data
RA George et al.
JOURNAL OF MOLECULAR BIOLOGY (2002)
Clinical presentation of genetically defined patients with hypokalemic salt-losing tubulopathies
M Peters et al.
AMERICAN JOURNAL OF MEDICINE (2002)
Hyperexcitability and epilepsy associated with disruption of the mouse neuronal-specific K-Cl cotransporter gene
NS Woo et al.
HIPPOCAMPUS (2002)
MST4, a new Ste20-related kinase that mediates cell growth and transformation via modulating ERK pathway
JL Lin et al.
ONCOGENE (2001)
Androgens induce expression of SPAK, a STE20/SPS1-related kinase, in LNCaP human prostate cancer cells
H Qi et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2001)
WNK kinases, a novel protein kinase subfamily in multi-cellular organisms
F Veríssimo et al.
ONCOGENE (2001)
Human hypertension caused by mutations in WNK kinases
FH Wilson et al.
SCIENCE (2001)
Kinetic and catalytic mechanisms of protein kinases
JA Adams
CHEMICAL REVIEWS (2001)
GABA itself promotes the developmental switch of neuronal GABAergic responses from excitation to inhibition
K Ganguly et al.
CELL (2001)
The Ste20 group kinases as regulators of MAP kinase cascades
I Dan et al.
TRENDS IN CELL BIOLOGY (2001)
AP-1 in cell proliferation and survival
E Shaulian et al.
ONCOGENE (2001)
Gene cloning of immunogenic antigens overexpressed in pancreatic cancer
T Nakatsura et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
Characterization of the apoptosis-associated tyrosine kinase (AATYK) expressed in the CNS
M Tomomura et al.
ONCOGENE (2001)
Characterization of an alternatively spliced AATYK mRNA: Expression pattern of AATYK in the brain and neuronal cells
SJ Baker et al.
ONCOGENE (2001)
A novel mouse Nedd4 protein suppresses the activity of the epithelial Na+ channel
E Kamynina et al.
FASEB JOURNAL (2001)
Fray, a Drosophila serine/threonine kinase homologous to mammalian PASK, is required for axonal ensheathment
WM Leiserson et al.
NEURON (2000)
Isolation and expression of PASK. a serine/threonine kinase, during rat embryonic development, with special emphasis on the pancreas
N Miao et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2000)
Protein kinase C isozymes and the regulation of diverse cell responses
EC Dempsey et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2000)
SPAK, a STE20/SPS1-related kinase that activates the p38 pathway
AM Johnston et al.
ONCOGENE (2000)
Flipping the switch: The structural basis for signaling through the CRIB motif
GR Hoffman et al.
CELL (2000)
NESK, a member of the germinal center kinase family that activates the c-Jun N-terminal kinase pathway and is expressed during the late stages of embryogenesis
K Nakano et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Vasopressin-mediated regulation of epithelial sodium channel abundance in rat kidney
CA Ecelbarger et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2000)
Modulation of the chaperone activities of Hsc70/Hsp40 by Hsp105α and Hsp105β
N Yamagishi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)
WNK1, a novel mammalian serine/threonine protein kinase lacking the catalytic lysine in subdomain II
BE Xu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
A novel kinase, AATYK induces and promotes neuronal differentiation in a human neuroblastoma (SH-SY5Y) cell line
M Raghunath et al.
MOLECULAR BRAIN RESEARCH (2000)
Molecular cloning of MINK, a novel member of mammalian GCK family kinases, which is up-regulated during postnatal mouse cerebral development
I Dan et al.
FEBS LETTERS (2000)
Aberrant CpG-island methylation has non-random and tumour-type-specific patterns
JF Costello et al.
NATURE GENETICS (2000)
OTOF encodes multiple long and short isoforms: Genetic evidence that the long ones underlie recessive deafness DFNB9
S Yasunaga et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2000)
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