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Precision-cut liver slices as a new model to study toxicity-induced hepatic stellate cell activation in a physiologic milieu
M van de Bovenkamp et al.
TOXICOLOGICAL SCIENCES (2005)
Anandamide induces necrosis in primary hepatic stellate cells
SV Siegmund et al.
HEPATOLOGY (2005)
Pregnenolone-16α-carbonitrile inhibits rodent liver fibrogenesis via PXR (pregnane X receptor)-dependent and PXR-independent mechanisms
CJ Marek et al.
BIOCHEMICAL JOURNAL (2005)
Novel sulfasalazine analogues with enhanced NF-kB inhibitory and apoptosis promoting activity
F Habens et al.
APOPTOSIS (2005)
HCV core protein promotes liver fibrogenesis via up-regulation of CTGF with TGF-β1
JY Shin et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2005)
Role of CD44 in epithelial wound repair - Migration of rat hepatic stellate cells utilizes hyaluronic acid and CD44v6
S Kikuchi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
The role of matrix stiffness in hepatic stellate cell activation and liver fibrosis
RG Wells
JOURNAL OF CLINICAL GASTROENTEROLOGY (2005)
Interleukin-6 protects hepatocytes from CCl4-mediated necrosis and apoptosis in mice by reducing MMP-2 expression
MB Bansal et al.
JOURNAL OF HEPATOLOGY (2005)
Growth inhibition and apoptosis in liver myofibroblasts promoted by hepatocyte growth factor leads to resolution from liver cirrhosis
WH Kim et al.
AMERICAN JOURNAL OF PATHOLOGY (2005)
Hepatic stellate cells and fibrosis progression in patients with nonalcoholic fatty liver disease
AE Feldstein et al.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2005)
Nuclear factor-κβ1 (p50) limits the inflammatory and fibrogenic responses to chronic injury
F Oakley et al.
AMERICAN JOURNAL OF PATHOLOGY (2005)
Antifibrogenic role of the cannabinoid receptor CB2 in the liver
B Julien et al.
GASTROENTEROLOGY (2005)
A germline DNA polymorphism enhances alternative splicing of the KLF6 tumor suppressor gene and is associated with increased prostate cancer risk
G Narla et al.
CANCER RESEARCH (2005)
Adipogenic transcriptional regulation of hepatic stellate cells
HY She et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Molecular profiling of early stage liver fibrosis in patients with chronic hepatitis C virus infection
I Bièche et al.
VIROLOGY (2005)
Coffee and caffeine consumption reduce the risk of elevated serum alanine aminotransferase activity in the United States
CE Ruhl et al.
GASTROENTEROLOGY (2005)
Inhibition of inhibitor of kappa B kinases stimulates hepatic stellate cell apoptosis and accelerated recovery from rat liver fibrosis
F Oakley et al.
GASTROENTEROLOGY (2005)
Merging models of hepatitis C virus pathogenesis
HL Tillmann et al.
SEMINARS IN LIVER DISEASE (2005)
Prediction of liver fibrosis and cirrhosis in chronic hepatitis B infection by serum proteomic fingerprinting: A pilot study
TCW Poon et al.
CLINICAL CHEMISTRY (2005)
Hepatotoxicity of iron overload: Mechanisms of iron-induced hepatic fibrogenesis
GA Ramm et al.
SEMINARS IN LIVER DISEASE (2005)
Liver fibrogenesis: A new role for the renin-angiotensin system
R Bataller et al.
ANTIOXIDANTS & REDOX SIGNALING (2005)
Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair
JS Duffield et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
Human hepatic stellate cell lines, LX-1 and LX-2: new tools for analysis of hepatic fibrosis
L Xu et al.
GUT (2005)
Kruppel-Like factor 6 (KLF6) is a tumor-suppressor gene frequently inactivated in colorectal cancer
HL Reeves et al.
GASTROENTEROLOGY (2004)
PPARs and the complex journey to obesity
RM Evans et al.
NATURE MEDICINE (2004)
Noninvasive diagnosis of liver cirrhosis using DNA sequencer-based total serum protein glycomics
N Callewaert et al.
NATURE MEDICINE (2004)
Connective tissue growth factor (CCN2) induces adhesion of rat activated hepatic stellate cells by binding of its C-terminal domain to integrin αvβ3 and heparan sulfate proteoglycan
RP Gao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Distinct roles of Smad2-, Smad3-, and ERK-dependent pathways in transforming growth factor-β1 regulation of pancreatic stellate cellular functions
H Ohnishi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Pioglitazone prevents alcohol-induced fatty liver in rats through up-regulation of c-Met
K Tomita et al.
GASTROENTEROLOGY (2004)
Clinical proteomics: Revolutionizing disease detection and patient tailoring therapy
E Petricoin et al.
JOURNAL OF PROTEOME RESEARCH (2004)
Hepatic fibrogenesis requires sympathetic neurotransmitters
JA Oben et al.
GUT (2004)
The caspase inhibitor IDN-6556 attenuates hepatic injury and fibrosis in the bile duct ligated mouse
A Canbay et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2004)
Pioglitazone prevents hepatic steatosis, fibrosis, and enzyme-altered lesions in rat liver cirrhosis induced by a choline-deficient L-amino acid-defined diet
K Kawaguchi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
Essential role of matrix metalloproteinases in interleukin-1-induced myofibroblastic activation of hepatic stellate cell in collagen
YP Han et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Induction of myofibroblast MMP-9 transcription in three-dimensional collagen I gel cultures:: regulation by NF-κB, AP-1 and Sp1
T Takahra et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2004)
Searching for common stem cells of the hepatic and hematopoietic systems in the human fetal liver:: CD34+ cytokeratin 7/8+ cells express markers for stellate cells
DL Suskind et al.
JOURNAL OF HEPATOLOGY (2004)
TRAM2 protein interacts with endoplasmic reticulum Ca2+ pump Serca2b and is necessary for collagen type I synthesis
B Stefanovic et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Commitment of bone marrow cells to hepatic stellate cells in mouse
S Baba et al.
JOURNAL OF HEPATOLOGY (2004)
PAR1 antagonism protects against experimental liver fibrosis.: Role of proteinase receptors in stellate cell activation
S Fiorucci et al.
HEPATOLOGY (2004)
Beneficial effect of angiotensin-blocking agents on graft fibrosis in hepatitis C recurrence after liver transplantation
A Rimola et al.
TRANSPLANTATION (2004)
Immune stimulation of hepatic fibrogenesis by CD8 cells and attenuation by transgenic interleukin-10 from hepatocytes
R Safadi et al.
GASTROENTEROLOGY (2004)
Neuroregulation of the neuroendocrine compartment of the liver
T Roskams et al.
ANATOMICAL RECORD PART A-DISCOVERIES IN MOLECULAR CELLULAR AND EVOLUTIONARY BIOLOGY (2004)
Molecular mechanisms regulating the antifibrogenic protein heme-oxygenase-1 in human hepatic myofibroblasts
LY Li et al.
JOURNAL OF HEPATOLOGY (2004)
Leptin as a novel profibrogenic cytokine in hepatic stellate cells: mitogenesis and inhibition of apoptosis mediated by extracellular regulated kinase (Erk) and Akt phosphorylation
NK Saxena et al.
FASEB JOURNAL (2004)
Expression of somatostatin receptors in normal and cirrhotic human liver and in hepatocellular carcinoma
H Reynaert et al.
GUT (2004)
Expression of P2Y nucleotide receptors and ectonucleotidases in quiescent and activated rat hepatic stellate cells
JA Dranoff et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2004)
Inhibition of T-cell responses by hepatic stellate cells via B7-H1-mediated T-cell apoptosis in mice
MC Yu et al.
HEPATOLOGY (2004)
Cytoglobin/STAP, its unique localization in splanchnic fibroblast-like cells and function in organ fibrogenesis
K Nakatani et al.
LABORATORY INVESTIGATION (2004)
Progression of liver fibrosis in women infected with hepatitis C: Long-term benefit of estrogen exposure
V Di Martino et al.
HEPATOLOGY (2004)
Lhx2-/- mice develop liver fibrosis
E Wandzioch et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Engagement of αvβ3 integrin regulates proliferation and apoptosis of hepatic stellate cells
XY Zhou et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Increased hepatic platelet activating factor (PAF) and PAF receptors in carbon tetrachloride induced liver cirrhosis
Y Yang et al.
GUT (2004)
Corticosteroids stimulate selectively transforming growth factor (TGF)-beta receptor type III expression in transdifferentiating hepatic stellate cells
L Wickert et al.
JOURNAL OF HEPATOLOGY (2004)
A pilot study of ploglitazone treatment for nonalcoholic steatohepatitis
K Promrat et al.
HEPATOLOGY (2004)
Expression of subtypes of somatostatin receptors in hepatic stellate cells
Sheng-Han Song et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2004)
Differential modulation of rat hepatic stellate phenotype by natural and synthetic retinoids
K Hellemams et al.
HEPATOLOGY (2004)
A dual reporter gene transgenic mouse demonstrates heterogeneity in hepatic fibrogenic cell populations
ST Magness et al.
HEPATOLOGY (2004)
Frequent inactivation of the tumor suppressor Kruppel-like factor 6 (KLF6) in hepatocellular carcinoma
S Kremer-Tal et al.
HEPATOLOGY (2004)
Association of differentially expressed genes with activation of mouse hepatic stellate cells by high-density cDNA mircoarray
Xiao-Jing Liu et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2004)
The nuclear receptor SHP mediates inhibition of hepatic stellate cells by FXR and protects against liver fibrosis
S Fiorucci et al.
GASTROENTEROLOGY (2004)
Molecular classification of liver cirrhosis in a rat model by proteomics and bioinformatics
XQ Xu et al.
PROTEOMICS (2004)
Regulation of α1(I) collagen messenger RNA decay by interactions with αCP at the 3′-untranslated region
JN Lindquist et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Superoxide-induced apoptosis of activated rat hepatic stellate cells
C Thirunavukkarasu et al.
JOURNAL OF HEPATOLOGY (2004)
Activated hepatic stellate cells express keratinocyte growth factor in chronic liver disease
H Steiling et al.
AMERICAN JOURNAL OF PATHOLOGY (2004)
Expression of leptin and leptin receptor during the development of liver fibrosis and cirrhosis
C Otte et al.
EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES (2004)
CD14-positive hepatic monocytes/macrophages increase in hereditary hemochromatosis
KL Leicester et al.
LIVER INTERNATIONAL (2004)
Epithelial-mesenchymal transition and its implications for fibrosis
R Kalluri et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
Enhanced carbon tetrachloride-induced liver fibrosis in mice lacking adiponectin
Y Kamada et al.
GASTROENTEROLOGY (2003)
Kupffer cell engulfment of apoptotic bodies stimulates death ligand and cytokine expression
A Canbay et al.
HEPATOLOGY (2003)
Stellate cell activation in alcoholic pancreatitis
MV Apte et al.
PANCREAS (2003)
Role of fibroblast growth factor type 1 and 2 in carbon tetrachloride-induced hepatic injury and fibrogenesis
CD Yu et al.
AMERICAN JOURNAL OF PATHOLOGY (2003)
The chemokine CCL21 modulates lymphocyte recruitment and fibrosis in chronic hepatitis C
A Bonacchi et al.
GASTROENTEROLOGY (2003)
Oxidative stress, KLF6 and transforming growth factor-β up-regulation differentiate non-alcoholic steatohepatitis progressing to fibrosis from uncomplicated steatosis in rats
P Stärkel et al.
JOURNAL OF HEPATOLOGY (2003)
Vascular endothelial growth factor and receptor interaction is a prerequisite for murine hepatic fibrogenesis
H Yoshiji et al.
GUT (2003)
Novel differential gene expression in human cirrhosis detected by suppression subtractive hybridization
NA Shackel et al.
HEPATOLOGY (2003)
Transforming growth factor-β1 downregulation of Smad1 gene expression in rat hepatic stellate cells
H Shen et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2003)
Prolonged infusion of angiotensin II into normal rats induces stellate cell activation and proinflammatory events in liver
R Bataller et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2003)
Ethanol induces transforming growth factor-α expression in hepatocytes, leading to stimulation of collagen synthesis by hepatic stellate cells
J Kato et al.
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH (2003)
BMP-7 counteracts TGF-β1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury
M Zeisberg et al.
NATURE MEDICINE (2003)
Activated human hepatic stellate cells express the renin-angiotensin system and synthesize angiotensin II
R Bataller et al.
GASTROENTEROLOGY (2003)
Smad7 prevents activation of hepatic stellate cells and liver fibrosis in rats
S Dooley et al.
GASTROENTEROLOGY (2003)
Establishment of immortalized human hepatic stellate scavenger cells to develop bioartificial livers
T Watanabe et al.
TRANSPLANTATION (2003)
Reciprocal modulation of matrix metalloproteinase-13 and type I collagen genes in rat hepatic stellate cells
B Schaefer et al.
AMERICAN JOURNAL OF PATHOLOGY (2003)
Iron-induced oxidant stress in alcoholic liver fibrogenesis
A Pietrangelo
ALCOHOL (2003)
Connective tissue growth factor (CTGF/CCN2) in hepatic fibrosis
AW Rachfal et al.
HEPATOLOGY RESEARCH (2003)
Toll-like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharide in human hepatic stellate cells
YH Paik et al.
HEPATOLOGY (2003)
Serum biomarkers of hepatitis B virus infected liver inflammation: A proteomic study
QY He et al.
PROTEOMICS (2003)
The normal liver harbors the vitamin D nuclear receptor in nonparenchymal and biliary epithelial cells
M Gascon-Barré et al.
HEPATOLOGY (2003)
Basement membrane-like matrix inhibits proliferation and collagen synthesis by activated rat hepatic stellate cells:: evidence for matrix-dependent deactivation of stellate cells
MDA Gaça et al.
MATRIX BIOLOGY (2003)
Apoptotic body engulfment by a human stellate cell line is profibrogenic
A Canbay et al.
LABORATORY INVESTIGATION (2003)
Interim results of a pilot study demonstrating the early effects of the PPAR-γ ligand rosiglitazone on insulin sensitivity, aminotransferases, hepatic steatosis and body weight in patients with non-alcoholic steatohepatitis
BA Neuschwander-Tetri et al.
JOURNAL OF HEPATOLOGY (2003)
Smads 2 and 3 are differentially activated by transforming growth factor-β (TGF-β) in quiescent and activated hepatic stellate cells -: Constitutive nuclear localization of Smads in activated cells is TGF-β-independent
CH Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Replicative senescence of activated human hepatic stellate cells is accompanied by a pronounced inflammatory but less fibrogenic phenotype
B Schnabl et al.
HEPATOLOGY (2003)
A comparison of fibrosis progression in chronic liver diseases
T Poynard et al.
JOURNAL OF HEPATOLOGY (2003)
Proangiogenic role of tumor-activated hepatic stellate cells in experimental melanoma metastasis
E Olaso et al.
HEPATOLOGY (2003)
Antifibrogenic effects of canrenone, an antialdosteronic drug, on human hepatic stellate cells
A Caligiuri et al.
GASTROENTEROLOGY (2003)
Impact of oestrogens on the progression of liver disease
I Shimizu
LIVER INTERNATIONAL (2003)
The myofibroblastic conversion of peribiliary fibrogenic cells distinct from hepatic stellate cells is stimulated by platelet-derived growth factor during liver fibrogenesis
N Kinnman et al.
LABORATORY INVESTIGATION (2003)
Selective Na+/H+ exchange inhibition by cariporide reduces liver fibrosis in the rat
A Di Sario et al.
HEPATOLOGY (2003)
Human hepatic stellate cells express CCR5 and RANTES to induce proliferation and migration
RF Schwabe et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2003)
Hepatocytes express nerve growth factor during liver injury - Evidence for paracrine regulation of hepatic stellate cell apoptosis
F Oakley et al.
AMERICAN JOURNAL OF PATHOLOGY (2003)
Vascular mediators in the injured liver
DC Rockey
HEPATOLOGY (2003)
Activated stellate cells express the TRAIL receptor-2/death receptor-5 and undergo TRAIL-mediated apoptosis
P Taimr et al.
HEPATOLOGY (2003)
Foxf1 +/- mice exhibit defective stellate cell activation and abnormal liver regeneration following CCl4 injury
VV Kalinichenko et al.
HEPATOLOGY (2003)
Peroxisome proliferator-activated receptor-beta signaling contributes to enhanced proliferation of hepatic stellate cells
K Hellemans et al.
GASTROENTEROLOGY (2003)
Mechanisms controlling early development of the liver
SA Duncan
MECHANISMS OF DEVELOPMENT (2003)
Activation of autoreactive B cells by CpG dsDNA
GA Viglianti et al.
IMMUNITY (2003)
Low density lipoprotein receptor-related protein (LRP) is a heparin-dependent adhesion receptor for connective tissue growth factor (CTGF) in rat activated hepatic stellate cells
RP Gao et al.
HEPATOLOGY RESEARCH (2003)
Establishment of an immortalized human hepatic stellate cell line to develop antifibrotic therapies
N Shibata et al.
CELL TRANSPLANTATION (2003)
Proteomic analysis of the rat liver
M Fountoulakis et al.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2002)
Transcriptional activation of endoglin and transforming growth factor-β signaling components by cooperative interaction between Sp1 and KLF6:: their potential role in the response to vascular injury
LM Botella et al.
BLOOD (2002)
Actin filament formation, reorganization and migration are impaired in hepatic stellate cells under influence of trichostatin A, a histone deacetylase inhibitor
K Rombouts et al.
JOURNAL OF HEPATOLOGY (2002)
Elevated expression of tyrosine kinase DDR2 in primary biliary cirrhosis
TK Mao et al.
AUTOIMMUNITY (2002)
Emerging concepts in inflammation and fibrosis
MC Gutiérrez-Ruíz et al.
ARCHIVES OF MEDICAL RESEARCH (2002)
Leptin enhances the effect of transforming growth factor in increasing type I collagen formation
M Tang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)
Fas enhances fibrogenesis in the bile duct ligated mouse: A link between apoptosis and fibrosis
A Canbay et al.
GASTROENTEROLOGY (2002)
Tissue inhibitor of metalloproteinases-1 attenuates spontaneous liver fibrosis resolution in the Transgenic mouse
H Yoshiji et al.
HEPATOLOGY (2002)
Estrogen reduces CCL4- induced liver fibrosis in rats
JW Xu et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2002)
Treatment of the rat hepatic stellate cell line, PAV-1, by retinol and palmitic acid leads to a convenient model to study retinoids metabolism
P Sauvant et al.
BIOLOGY OF THE CELL (2002)
Characterization of human stellate cell activation-associated protein and its expression in human liver
K Asahina et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION (2002)
Organotypic liver culture in a fluid-air interface using slices of neonatal rat and adult human tissue - a model of fibrosis in vitro
C Verrill et al.
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS (2002)
Expression of transmembrane 4 superfamily (TM4SF) proteins and their role in hepatic stellate cell motility and wound healing migration
A Mazzocca et al.
JOURNAL OF HEPATOLOGY (2002)
Caspase 9-dependent killing of hepatic stellate cells by activated Kupffer cells
R Fischer et al.
GASTROENTEROLOGY (2002)
Cell adhesion regulates platelet-derived growth factor-induced MAP kinase and PI-3 kinase activation in stellate cells
V Carloni et al.
HEPATOLOGY (2002)
Sp1 and Sp3 transcription factors mediate malondialdehyde-induced collagen α1(I) gene expression in cultured hepatic stellate cells
I García-Ruiz et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
The vagal nerve stimulates activation of the hepatic progenitor cell compartment via muscarinic acetylcholine receptor type 3
D Cassiman et al.
AMERICAN JOURNAL OF PATHOLOGY (2002)
PAV-1, a new rat hepatic stellate cell line converts retinol into retinoic acid, a process altered by ethanol
P Sauvant et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2002)
Regulatory phases of early liver development: Paradigms of organogenesis
KS Zaret
NATURE REVIEWS GENETICS (2002)
Impaired liver regeneration in mice by lipopolysaccharide via TNF-α/kallikrein-mediated activation of latent TGF-β
K Akita et al.
GASTROENTEROLOGY (2002)
Effects and regulation of connective tissue growth factor on hepatic stellate cells
V Paradis et al.
LABORATORY INVESTIGATION (2002)
Transcriptional regulation of hepatic stellate cell activation
DA Mann et al.
GUT (2002)
The correlation between portal myofibroblasts and development of intrahepatic bile ducts and arterial branches in human liver
L Libbrecht et al.
LIVER (2002)
Pleiotrophin/heparin-binding growth-associated molecule as a mitogen of rat hepatocytes and its role in regeneration and development of liver
K Asahina et al.
AMERICAN JOURNAL OF PATHOLOGY (2002)
Antidiabetic thiazolidinediones inhibit collagen synthesis and hepatic stellate cell activation in vivo and in vitro
A Galli et al.
GASTROENTEROLOGY (2002)
Discoidin domain receptor 2 interacts with Src and Shc following its activation by type I collagen
K Ikeda et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Regulation of the murine α2(I) collagen promoter by retinoic acid and retinoid X receptors
L Wang et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2002)
Leptin receptor-mediated signaling regulates hepatic fibrogenesis and remodeling of extracellular matrix in the rat
K Ikejima et al.
GASTROENTEROLOGY (2002)
Hypoxia-induced VEGF and collagen I expressions are associated with angiogenesis and fibrogenesis in experimental cirrhosis
C Corpechot et al.
HEPATOLOGY (2002)
Enhanced expression of endothelial nitric oxide synthase and caveolin-1 in human cirrhosis
H Yokomori et al.
LIVER (2002)
Leptin in hepatic fibrosis:: Evidence for increased collagen production in stellate cells and lean littermates of ob/ob mice
NK Saxena et al.
HEPATOLOGY (2002)
Hepatic stellate cells: role in microcirculation and pathophysiology of portal hypertension
H Reynaert et al.
GUT (2002)
Inhibition of apoptosis of activated hepatic stellate cells by tissue inhibitor of metalloproteinase-1 is mediated via effects on matrix metalloproteinase inhibition - Implications for reversibility of liver fibrosis
FR Murphy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Cytochrome P450 2E1-derived reactive oxygen species mediate paracrine stimulation of collagen I protein synthesis by hepatic stellate cells
N Nieto et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Delayed liver regeneration with negative regulation of hepatocyte growth factor and positive regulation of transforming growth factor-betal mRNA after portal branch ligation in biliary obstructed rats
T Yamano et al.
SURGERY (2002)
Insights into the pathobiology of hepatitis C virus-associated cirrhosis - Analysis of intrahepatic differential gene expression
NA Shackel et al.
AMERICAN JOURNAL OF PATHOLOGY (2002)
Hepatocyte growth factor induces collagenase (matrix metalloproteinase-1) via the transcription factor Ets-1 in human hepatic stellate cell line
I Ozaki et al.
JOURNAL OF HEPATOLOGY (2002)
Hepatocyte growth factor and c-met inhibition by hepatic cell hypoxia - A potential mechanism for liver regeneration failure in experimental cirrhosis
C Corpechot et al.
AMERICAN JOURNAL OF PATHOLOGY (2002)
Immortal activated human hepatic stellate cells generated by ectopic telomerase expression
B Schnabl et al.
LABORATORY INVESTIGATION (2002)
Regulation of hepatic stellate cell proliferation and collagen synthesis by proteinase-activated receptors
MDA Gaca et al.
JOURNAL OF HEPATOLOGY (2002)
Differential regulation of TGF-beta signal in hepatic stellate cells between acute and chronic rat liver injury
Y Tahashi et al.
HEPATOLOGY (2002)
Stimulation and proliferation of primary rat hepatic stellate cells by cytochrome P450 2E1-derived reactive oxygen species
N Nieto et al.
HEPATOLOGY (2002)
KLF6, a candidate tumor suppressor gene mutated in prostate cancer
G Narla et al.
SCIENCE (2001)
Hepatic stellate cell proliferation is an early platelet-derived growth factor-mediated cellular event in rat cholestatic liver injury
N Kinnman et al.
LABORATORY INVESTIGATION (2001)
N-acetylcysteine induces cell cycle arrest in hepatic stellate cells through its reducing activity
KY Kim et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Up-regulated expression of the receptor for advanced glycation end products in cultured rat hepatic stellate cells during transdifferentiation to myofibroblasts
H Fehrenbach et al.
HEPATOLOGY (2001)
Liver organogenesis promoted by endothelial cells prior to vascular function
K Matsumoto et al.
SCIENCE (2001)
Oxidized low-density lipoproteins bind to the scavenger receptor, CD36, of hepatic stellate cells and stimulate extracellular matrix synthesis
W Schneiderhan et al.
HEPATOLOGY (2001)
High glucose and hyperinsulinemia stimulate connective tissue growth factor expression: A potential mechanism involved in progression to fibrosis in nonalcoholic steatohepatitis
V Paradis et al.
HEPATOLOGY (2001)
Targeting dexamethasone to Kupffer cells: Effects on liver inflammation and fibrosis in rats
BN Melgert et al.
HEPATOLOGY (2001)
Malondialdehyde-acetaldehyde-protein adducts increase secretion of chemokines by rat hepatic stellate cells
KK Kharbanda et al.
ALCOHOL (2001)
Kruppel-like factors: Three fingers in many pies
JJ Bieker
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Extracellular matrix degradation and the role of hepatic stellate cells
RC Benyon et al.
SEMINARS IN LIVER DISEASE (2001)
Matrix as a modulator of hepatic fibrogenesis
D Schuppan et al.
SEMINARS IN LIVER DISEASE (2001)
Hepatic blood flow regulation by stellate cells in normal and injured liver
DC Rockey
SEMINARS IN LIVER DISEASE (2001)
Cytokine receptors and signaling in hepatic stellate cells
M Pinzani et al.
SEMINARS IN LIVER DISEASE (2001)
Interactions between hepatic stellate cells and the immune system
JJ Maher
SEMINARS IN LIVER DISEASE (2001)
Hepatic stellate cell behavior during resolution of liver injury
JP Iredale
SEMINARS IN LIVER DISEASE (2001)
Leptin augments inflammatory and profibrogenic responses in the murine liver induced by hepatotoxic chemicals
K Ikejima et al.
HEPATOLOGY (2001)
History, heterogeneity, developmental biology, and functions of quiescent hepatic stellate cells
A Geerts
SEMINARS IN LIVER DISEASE (2001)
Transcriptional regulation in hepatic stellate cells
FJ Eng et al.
SEMINARS IN LIVER DISEASE (2001)
Characterization of a stellate cell activation-associated protein (STAP) with peroxidase activity found in rat hepatic stellate cells
N Kawada et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Attenuation of CCl4-induced hepatic fibrosis by GdCl3 treatment or dietary glycine
CA Rivera et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2001)
Angiotensin-converting enzyme inhibition attenuates the progression of rat hepatic fibrosis
JR Jonsson et al.
GASTROENTEROLOGY (2001)
JunD regulates transcription of the tissue inhibitor of metalloproteinases-1 and interleukin-6 genes in activated hepatic stellate cells
DE Smart et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
CD40 activates NF-κB and c-Jun N-terminal kinase and enhances chemokine secretion on activated human hepatic stellate cells
RF Schwabe et al.
JOURNAL OF IMMUNOLOGY (2001)
Lipid peroxidation in hepatic steatosis in humans is associated with hepatic fibrosis and occurs predominately in acinar zone 3
GA Macdonald et al.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2001)
The Hedgehog and Wnt signaling pathways in cancer
J Taipale et al.
NATURE (2001)
Disease-induced drug targeting using novel peptide-ligand albumins
DKF Meijer et al.
JOURNAL OF CONTROLLED RELEASE (2001)
Expression of Smads during in vitro transdifferentiation of hepatic stellate cells to myofibroblasts
S Dooley et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
The collagen receptor DDR2 regulates proliferation and its elimination leads to dwarfism
JP Labrador et al.
EMBO REPORTS (2001)
AP-1 in mouse development and tumorigenesis
W Jochum et al.
ONCOGENE (2001)
Aldehydes potentiate α2(I) collagen gene activity by JNK in hepatic stellate cells
FA Anania et al.
FREE RADICAL BIOLOGY AND MEDICINE (2001)
Apoptosis of hepatic stellate cells: involvement in resolution of biliary fibrosis and regulation by soluble growth factors
R Issa et al.
GUT (2001)
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