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JOURNAL OF ENDOCRINOLOGY (2004)
Ceramide induces release of pro-apoptotic proteins from mitochondria by either a Ca2+-dependent or a Ca2+-independent mechanism
M Di Paola et al.
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES (2004)
Cardiovascular consequences of sleep-disordered breathing: Past, present and future - Report of a workshop from the National Center on Sleep Disorders Research and the National Heart, Lung, and Blood Institute
SF Quan et al.
CIRCULATION (2004)
Inflammation and chronic heart failure -: potential therapeutic role of intravenous immunoglobulin
P Aukrust et al.
AUTOIMMUNITY REVIEWS (2004)
Body morphology differentially predicts coronary calcium
MA Allison et al.
INTERNATIONAL JOURNAL OF OBESITY (2004)
Treatment of type 2 diabetic db/db mice with a novel PPARγ agonist improves cardiac metabolism but not contractile function
AN Carley et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2004)
Apolipoprotein B production reduces lipotoxic cardiomyopathy - Studies in heart-specific lipoprotein lipase transgenic mouse
M Yokoyama et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Angiotensin-converting enzyme inhibition and angiogenesis in myocardium of obese Zucker rats
JE Toblli et al.
AMERICAN JOURNAL OF HYPERTENSION (2004)
Long-term caspase inhibition ameliorates apoptosis, reduces myocardial troponin-I cleavage, protects left ventricular function, and attenuates remodeling in rats with myocardial infarction
Y Chandrashekhar et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2004)
Adapted changes in left ventricular structure and function in severe uncomplicated obesity
G Iacobellis et al.
OBESITY RESEARCH (2004)
Hyperleptinemia prevents lipotoxic cardiomyopathy in acyl CoA synthase transgenic mice
Y Lee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Leptin induces hypertrophy via endothelin-1-reactive oxygen species pathway in cultured neonatal rat cardiomyocytes
FP Xu et al.
CIRCULATION (2004)
Impaired cardiac efficiency and increased fatty acid oxidation in insulin-resistant ob/ob mouse hearts
PK Mazumder et al.
DIABETES (2004)
Impact of obesity on the risk of heart failure and survival after the onset of heart failure
S Kenchaiah et al.
MEDICAL CLINICS OF NORTH AMERICA (2004)
Salutary effects of attenuation of angiotensin II on coronary perivascular fibrosis associated with insulin resistance and obesity
AKMT Zaman et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2004)
Region-specific reduction in leptin-induced phosphorylation of signal transducer and activator of transcription-3 (STAT3) in the rat hypothalamus is associated with leptin resistance during pregnancy
SR Ladyman et al.
ENDOCRINOLOGY (2004)
Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery
L Sjöström et al.
NEW ENGLAND JOURNAL OF MEDICINE (2004)
Gender differences in hypertrophy, insulin resistance and ischemic injury in the aging type 2 diabetic rat heart
M Desrois et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2004)
True uncomplicated obesity is not related to increased left ventricular mass and systolic dysfunction
G Iacobellis
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2004)
Caspase inhibition attenuates contractile dysfunction following cardioplegic arrest and Rewarming in the setting of left ventricular failure
WM Yarbrough et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2004)
Adiponectin-mediated modulation of hypertrophic signals in the heart
R Shibata et al.
NATURE MEDICINE (2004)
Rat heart is a site of leptin production and action
DM Purdham et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2004)
Insulin signaling in heart muscle: Lessons from genetically engineered mouse models
ED Abel
CURRENT HYPERTENSION REPORTS (2004)
Obesity and the risk of new-onset atrial fibrillation
TJ Wang et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2004)
Weight loss-associated induction of peroxisome proliferator-activated receptor-α and peroxisome proliferator-activated receptor-γ correlate with reduced atherosclerosis and improved cardiovascular function in obese insulin-resistant mice
W Verreth et al.
CIRCULATION (2004)
Enhanced sarcolemmal FAT/CD36 content and triacylglycerol storage in cardiac myocytes from obese Zucker rats
SLM Coort et al.
DIABETES (2004)
Alterations of left ventricular myocardial characteristics associated with obesity
CY Wong et al.
CIRCULATION (2004)
Absence of an effect of liposuction on insulin action and risk factors for coronary heart disease
S Klein et al.
NEW ENGLAND JOURNAL OF MEDICINE (2004)
Clinical implications of obesity with specific focus on cardiovascular disease - A statement for professionals from the American Heart Association Council on Nutrition, Physical Activity, and Metabolism - Endorsed by the American College of Cardiology Foundation
S Klein et al.
CIRCULATION (2004)
Comparison of right and left ventricular function in obese and nonobese men
ME Otto et al.
AMERICAN JOURNAL OF CARDIOLOGY (2004)
Cardiac mitochondrial damage and biogenesis in a chronic model of type 1 diabetes
X Shen et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2004)
Intramyocardial lipid accumulation in the failing human heart resembles the lipotoxic rat heart
S Sharma et al.
FASEB JOURNAL (2004)
The relation of obesity throughout life to carotid intima-media thickness in adulthood: the Bogalusa Heart Study
DS Freedman et al.
INTERNATIONAL JOURNAL OF OBESITY (2004)
Region-specific leptin resistance within the hypothalamus of diet-induced obese mice
H Münzberg et al.
ENDOCRINOLOGY (2004)
Obesity, metabolic syndrome, and type 2 diabetes: emerging epidemics and their cardiovascular implications
GA Mensah et al.
CARDIOLOGY CLINICS (2004)
Adipose tissue as an endocrine organ
EE Kershaw et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2004)
Cardiomyocyte-restricted peroxisome proliferator-activated receptor-δ deletion perturbs myocardial fatty acid oxidation and leads to cardiomyopathy
LH Cheng et al.
NATURE MEDICINE (2004)
gAd-globular head domain of adiponectin increases fatty acid oxidation in newborn rabbit hearts
A Onay-Besikci et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Obesity-related hypertension: Is there a role for selective leptin resistance?
MLG Correia et al.
CURRENT HYPERTENSION REPORTS (2004)
Optimal noninvasive assessment of left ventricular filling pressures - A comparison of tissue Doppler echocardiography and B-type natriuretic peptide in patients with pulmonary artery catheters
H Dokainish et al.
CIRCULATION (2004)
Associations among plasma adiponectin, hypertension, left ventricular diastolic function and left ventricular mass index
SJ Hong et al.
BLOOD PRESSURE (2004)
Myocardial hypertrophy and enhanced left ventricular contractility in Zucker diabetic fatty rats
S Fredersdorf et al.
CARDIOVASCULAR PATHOLOGY (2004)
Diabetic cardiomyopathy: Recent evidence from mouse models of type 1 and type 2 diabetes
DL Severson
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (2004)
Effect of obesity and insulin resistance on myocardial substrate metabolism and efficiency in young women
LR Peterson et al.
CIRCULATION (2004)
Obesity and suppressed B-type natriuretic peptide levels in heart failure
MR Mehra et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2004)
Onset of diabetes in Zucker diabetic fatty (ZDF) rats leads to improved recovery of function after ischemia in the isolated perfused heart
PP Wang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2004)
Loss of leptin actions in obesity: Two concepts with cardiovascular implications.
AL Mark et al.
CLINICAL AND EXPERIMENTAL HYPERTENSION (2004)
Effects of the sibutramine therapy on pulmonary artery pressure in obese patients
A Guven et al.
DIABETES OBESITY & METABOLISM (2004)
Pioglitazone, a peroxisome proliferator-activated receptor-γ agonist, attenuates myocardial ischernia/reperfusion injury in a rat model
H Ito et al.
LABORATORY INVESTIGATION (2003)
Effects of isolated obesity on systolic and diastolic left ventricular function
M Pascual et al.
HEART (2003)
Insulin resistance induces hyperleptinemia, cardiac contractile dysfunction but not cardiac leptin resistance in ventricular myocytes
KK Hintz et al.
INTERNATIONAL JOURNAL OF OBESITY (2003)
Quantitative protein profiling in heart mitochondria from diabetic rats
IV Turko et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Protein tyrosine nitration in the mitochondria from diabetic mouse heart - Implications to dysfunctional mitochondria in diabetes
IV Turko et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Minimally invasive aortic banding in mice: effects of altered cardiomyocyte insulin signaling during pressure overload
P Hu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2003)
Disruption of leptin signaling contributes to cardiac hypertrophy independently of body weight in mice
LA Barouch et al.
CIRCULATION (2003)
Cardiac lipid accumulation associated with diastolic dysfunction in obese mice
C Christoffersen et al.
ENDOCRINOLOGY (2003)
Left ventricular hypertrophy is a common echocardiographic abnormality in severe obstructive sleep apnea and reverses with nasal continuous positive airway pressure
TV Cloward et al.
CHEST (2003)
Diastolic dysfunction is associated with altered myocardial metabolism in asymptomatic normotensive patients with well-controlled type 2 diabetes mellitus
M Diamant et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2003)
Inhibition of granulation tissue cell apoptosis during the subacute stage of myocardial infarction improves cardiac remodeling and dysfunction at the chronic stage
K Hayakawa et al.
CIRCULATION (2003)
Abnormal cardiac and skeletal muscle energy metabolism in patients with type 2 diabetes
M Scheuermann-Freestone et al.
CIRCULATION (2003)
Myocytes die by multiple mechanisms in failing human hearts
S Kostin et al.
CIRCULATION RESEARCH (2003)
Mitochondrial effects with ceramide-induced cardiac apoptosis are different from those of palmitate
JY Kong et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2003)
Body composition and prognosis in chronic systolic heart failure: The obesity paradox
CJ Lavie et al.
AMERICAN JOURNAL OF CARDIOLOGY (2003)
Triglyceride accumulation protects against fatty acid-induced lipotoxicity
LL Listenberger et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Myocardial triglycerides and systolic function in humans: In vivo evaluation by localized proton spectroscopy and cardiac imaging
LS Szczepaniak et al.
MAGNETIC RESONANCE IN MEDICINE (2003)
A critical role for PPARα-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy:: Modulation by dietary fat content
BN Finck et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Age-dependent changes in metabolism, contractile function, and ischemic sensitivity in hearts from db/db mice
E Aasum et al.
DIABETES (2003)
Impact of glucose intolerance and insulin resistance on cardiac structure and function - Sex-related differences in the Framingham Heart Study
MK Rutter et al.
CIRCULATION (2003)
Alterations in nitric oxide-cGMP pathway in ventricular myocytes from obese leptin-deficient mice
J Su et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2003)
Pharmacologic inhibition of intracellular caspases after myocardial infarction attenuates left ventricular remodeling: A potentially novel pathway
WM Yarbrough et al.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY (2003)
Effects of hypertension and obesity on the sympathetic activation of heart failure patients
G Grassi et al.
HYPERTENSION (2003)
Obesity and type 2 diabetes
CA Maggio et al.
ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA (2003)
Role of adiponectin in preventing vascular stenosis - The missing link of adipo-vascular axis
M Matsuda et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Effects of sibutramine on ventricular dimensions and heart valves in obese patients during weight reduction
F Zannad et al.
AMERICAN HEART JOURNAL (2002)
Hypoxia-induced cleavage of caspase-3 and DFF45/ICAD in human failed cardiomyocytes
A Todor et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2002)
Echocardiographic assessment of cardiac function in diabetic db/db and transgenic db/db-hGLUT4 mice
LM Semeniuk et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2002)
Cardiac function and metabolism in Type 2 diabetic mice after treatment with BM 17.0744, a novel PPAR-α activator
E Aasum et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2002)
Impaired long-chain fatty acid oxidation and contractile dysfunction in the obese Zucker rat heart
ME Young et al.
DIABETES (2002)
The prognostic value of body mass index and standard exercise testing in male veterans with congestive heart failure
LW Lissin et al.
JOURNAL OF CARDIAC FAILURE (2002)
Obesity and the risk of heart failure
S Kenchaiah et al.
NEW ENGLAND JOURNAL OF MEDICINE (2002)
Influence of excess fat on cardiac morphology and function: Study in uncomplicated obesity
G Iacobellis et al.
OBESITY RESEARCH (2002)
Disruption of adiponectin causes insulin resistance and neointimal formation.
N Kubota et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Selective leptin resistance: a new concept in leptin physiology with cardiovascular implications
AL Mark et al.
JOURNAL OF HYPERTENSION (2002)
Diet-induced insulin resistance in mice lacking adiponectin/ACRP30
N Maeda et al.
NATURE MEDICINE (2002)
Obesity accelerates the progression of coronary atherosclerosis in young men
HC McGill et al.
CIRCULATION (2002)
Echocardiographic abnormalities in normotensive obese patients: Relationship with visceral fat
L Morricone et al.
OBESITY RESEARCH (2002)
Left ventricular hypertrophy and abnormal ventricular geometry in children and adolescents with obstructive sleep apnea
RS Amin et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2002)
Cardiac membrane fatty acid composition modulates myocardial oxygen consumption and postischemic recovery of contractile function
S Pepe et al.
CIRCULATION (2002)
Rosiglitazone, a peroxisome proliferator-activated receptor-γ, inhibits the Jun NH2-terminal kinase/activating protein 1 pathway and protects the heart from ischemia/reperfusion injury
N Khandoudi et al.
DIABETES (2002)
Functional consequences of caspase activation in cardiac myocytes
C Communal et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Thiazolidinedione treatment normalizes insulin resistance and ischemic injury in the Zucker fatty rat heart
RJ Sidell et al.
DIABETES (2002)
Mechanisms of lipoapoptosis: Implications for human heart disease
LL Listenberger et al.
TRENDS IN CARDIOVASCULAR MEDICINE (2002)
The impact of obesity on the short-term and long-term outcomes after percutaneous coronary intervention: The obesity paradox?
L Gruberg et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2002)
Selective resistance to central neural administration of leptin in agouti obese mice
K Rahmouni et al.
HYPERTENSION (2002)
The concept of selective leptin resistance - Evidence from agouti yellow obese mice
MLG Correia et al.
DIABETES (2002)
Decreased cardiac expression of vascular endothelial growth factor and its receptors in insulin-resistant and diabetic states - A possible explanation for impaired collateral formation in cardiac tissue
E Chou et al.
CIRCULATION (2002)
Myocardial infarction and coronary pathology in severely obese people examined at autopsy
ML Kortelainen
INTERNATIONAL JOURNAL OF OBESITY (2002)
Apoptosis in myocardial infarction
M Rodriguez et al.
ANNALS OF MEDICINE (2002)
In vivo myocardial protection from ischemia/reperfusion injury by the peroxisome proliferator-activated receptor-γ agonist rosiglitazone
TL Yue et al.
CIRCULATION (2001)
The relationship between obesity and mortality in patients with heart failure
TB Horwich et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2001)
The prognosis of heart failure in the general population - The Rotterdam Study
A Mosterd et al.
EUROPEAN HEART JOURNAL (2001)
Angiotensin-converting enzyme inhibition attenuates hypofibrinolysis and reduces cardiac perivascular fibrosis in genetically obese diabetic
AKMT Zaman et al.
CIRCULATION (2001)
Impact of obstructive sleep apnea on left ventricular mass and diastolic function
M Niroumand et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2001)
Palmitate-induced apoptosis can occur through a ceramide-independent pathway
LL Listenberger et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Time course of the apoptotic cascade and effects of caspase inhibitors in adult rat ventricular cardiomyocytes
K Suzuki et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2001)
Risk factors for congestive heart failure in US men and women -: NHANES I epidemiologic follow-up study
J He et al.
ARCHIVES OF INTERNAL MEDICINE (2001)
A novel mouse model of lipotoxic cardiomyopathy
HC Chiu et al.
JOURNAL OF CLINICAL INVESTIGATION (2001)
Heart failure in the general population of men - morbidity, risk factors and prognosis
L Wilhelmsen et al.
JOURNAL OF INTERNAL MEDICINE (2001)
Visceral fat and coronary pathology in male adolescents
ML Kortelainen et al.
INTERNATIONAL JOURNAL OF OBESITY (2001)
Obesity and insulin resistance
BB Kahn et al.
JOURNAL OF CLINICAL INVESTIGATION (2000)
Obesity and left ventricular diastolic function: noninvasive study in normotensives and newly diagnosed never-treated hypertensives
AM Grandi et al.
INTERNATIONAL JOURNAL OF OBESITY (2000)
Relief of cardiorespiratory symptoms and increased physical activity after surgically induced weight loss -: Results from the Swedish Obese Subjects Study
K Karason et al.
ARCHIVES OF INTERNAL MEDICINE (2000)
The association of human adipose angiotensinogen gene expression with abdominal fat distribution in obesity
V van Harmelen et al.
INTERNATIONAL JOURNAL OF OBESITY (2000)
Weight loss with sibutramine improves glycaemic control and other metabolic parameters in obese patients with type 2 diabetes mellitus
K Fujioka et al.
DIABETES OBESITY & METABOLISM (2000)
Physiology and pathophysiology of the adipose tissue renin-angiotensin system
S Engeli et al.
HYPERTENSION (2000)
Unresolved issues regarding the role of apoptosis in the pathogenesis of ischemic injury and heart failure
A Elsässer et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2000)
Lipotoxic heart disease in obese rats: Implications for human obesity
YT Zhou et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Pathophysiological role of leptin in obesity-related hypertension
M Aizawa-Abe et al.
JOURNAL OF CLINICAL INVESTIGATION (2000)
Involvement of caspase 3-and 8-like proteases in ceramide-induced apoptosis of cardiomyocytes
J Wang et al.
JOURNAL OF CARDIAC FAILURE (2000)
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