Enhanced Biodegradability of Pharmaceuticals and Personal Care Products by Ionizing Radiation

The radiolytic degradation of antibiotic compounds, including lincomycin (LMC), sulfamethoxazole (SMX), and tetracycline (TCN), and the change of biodegradability of the radiation-treated target compounds were evaluated. As a result, the degradation of target antibiotics by hydrolysis, biodegradation, and gamma irradiation showed a compound-dependent manner. However, the biodegradability of all target compounds was enhanced by the gamma irradiation. The enhanced biodegradability after gamma irradiation (2 kGy) followed the trend of LMC (18.89%), SMX (28.33%), TCN (36.62%), indicating that gamma irradiation might transform nonbiodegradable compounds into biodegradable. Consequently, the effective degradation of nonbiodegradable antibiotics can be accomplished by ionizing radiation followed by biodegradation. This result indicated that ionizing radiation technology would be useful to enhance biodegradability of the recalcitrant pollutants and can facilitate further degradation of residuals or intermediates in the effluent when discharged into surface water.