期刊
PHYSICS OF LIFE REVIEWS
卷 9, 期 3, 页码 219-263出版社
ELSEVIER
DOI: 10.1016/j.plrev.2012.06.001
关键词
RNA world; Early evolution; What is life; Protocell; Mathematical modeling; Computational modeling
资金
- Netherlands Organization for Scientific Research [612.060.522]
- Intramural Research Program of the NIH, National Library of Medicine
- JSPS
We review computational studies on prebiotic evolution, focusing on informatic processes in RNA-like replicator systems. In particular, we consider the following processes: the maintenance of information by replicators with and without interactions, the acquisition of information by replicators having a complex genotype phenotype map, the generation of information by replicators having a complex genotype phenotype interaction map, and the storage of information by replicators serving as dedicated templates. Focusing on these informatic aspects, we review studies on quasi-species, error threshold, RNA-folding genotype-phenotype map. hypercycle, multilevel selection (including spatial self-organization, classical group selection, and compartmentalization), and the origin of DNA-like replicators. In conclusion, we pose a future question for theoretical studies on the origin of life. Published by Elsevier B.V.
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