期刊
PHYSICS IN MEDICINE AND BIOLOGY
卷 53, 期 22, 页码 6291-6303出版社
IOP Publishing Ltd
DOI: 10.1088/0031-9155/53/22/002
关键词
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资金
- National Institutes of Health [R01CA117997]
- National Science Foundation [CCF-0515203, CBET-0755054]
- Div Of Chem, Bioeng, Env, & Transp Sys
- Directorate For Engineering [0755054] Funding Source: National Science Foundation
Arc-modulated radiation therapy (AMRT) is a novel rotational intensity-modulated radiation therapy (IMRT) technique developed for a clinical linear accelerator that aims to deliver highly conformal radiation treatment using just one arc of gantry rotation. Compared to fixed-gantry IMRT and the multiple-arc intensity-modulated arc therapy (IMAT) techniques, AMRT promises the same treatment quality with a single-arc delivery. In this paper, we present a treatment planning scheme for AMRT, which addresses the challenges in inverse planning, leaf sequencing and dose calculation. The feasibility and performance of this AMRT treatment planning scheme have been verified with multiple clinical cases of various sites on Varian linear accelerators.
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