期刊
VETERINARY JOURNAL
卷 206, 期 2, 页码 236-238出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.tvjl.2015.07.018
关键词
Sarcocystis neurona; Diclazuril; Prevention; Indirect fluorescence antibody test; Horses
资金
- Center for Equine Health, School of Veterinary Medicine, University of California, Davis [13-11]
Thirty-three foals from a farm with a high exposure rate to Sarcocystis neurona were assigned to either an untreated or a diclazuril-treated group. Treated foals received daily 0.5 mg/kg of diclazuril pellets from 1 to 12 months of age. Monthly blood was tested for IgG against S. neurona using the indirect fluorescent antibody test. Following ingestion of colostral antibodies to S. neurona, there was a steady and continuous decline in seroprevalence to S. neurona until foals from both groups reached weaning age. Thereafter, the untreated foal group showed a significant increase in monthly seroprevalence compared to the diclazuril-treated foal group. The difference in temporal seroprevalence could be explained by the successful reduction of S. neurona infection in foals receiving a daily low-dose diclazuril. (C) 2015 Elsevier Ltd. All rights reserved.
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