We show that in a microfluidic network with low Reynolds numbers, a system can be irreversible due to hysteresis effects. We simulated a network of pipes that was used in a recent experiment. The network consists of one loop connected to input and output pipes. A train of droplets enters the system at a uniform rate, but the droplets may leave the system in a periodic or even a chaotic pattern. The output pattern depends on the time interval between incoming droplets as well as the network geometry. For some parameters, the system is not reversible.
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