期刊
VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE
卷 45, 期 6, 页码 1159-+出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.cvsm.2015.06.003
关键词
ADAMTS10; ADAMTS17; Canine; Genetics; Glaucoma; Open-angle; Closed-angle; Lens luxation
资金
- Michigan State University Startup Funds
- Glaucoma Research Foundation
- Edward Sheppard and family
- Myers-Dunlap Endowment for Canine Health
Primary glaucomas are a leading cause of incurable vision loss in dogs. Based on their specific breed predilection, a genetic cause is suspected to be responsible, and affected dogs should be excluded from breeding. Despite the high prevalence of primary glaucomas in dogs, their genetics have been studied in only a small number of breeds. The identification of canine glaucoma disease genes, and the development of genetic tests, will help to avoid the breeding of affected dogs in the future and will allow for earlier diagnosis and potentially more effective therapy.
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