期刊
VECTOR-BORNE AND ZOONOTIC DISEASES
卷 15, 期 5, 页码 323-325出版社
MARY ANN LIEBERT, INC
DOI: 10.1089/vbz.2014.1748
关键词
Rickettsia africae; African tick-bite fever; Sudan; Real-time PCR; Size-based multispacer typing
资金
- Ministry of Education, Culture, Sports, Science and Technology of Japan (MEXT) [24880003, 25850195]
- Grants-in-Aid for Scientific Research [25850195, 24880003] Funding Source: KAKEN
Despite the increasing awareness of the importance of emerging vector-borne diseases, human tick-borne diseases, particularly rickettsial infections, are overlooked, especially in the countries such as Sudan with limited resources to perform molecular-based surveys. This study aimed at detection and genetic characterization of Rickettsia spp. in ticks collected from Sudan. The samples were first screened for the presence of rickettsial agents by gltA real-time PCR and subsequently characterized by gltA and ompA PCR and size-based multispacer typing. The results demonstrated the wide distribution of Rickettsia africae and/or closely related species across Sudan. The results of this report highlight the need for careful consideration of rickettsial infections in patients with nonmalarial febrile illness in this country. Nationwide surveillance on ticks associated with human rickettsial infections in Sudan is warranted.
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