期刊
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
卷 16, 期 18, 页码 8243-8246出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cp54518k
关键词
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资金
- FP7 EU Marie Curie Actions through the Campus Mare Nostrum 37/38 CMN UMU Incoming Mobility Programme ACTion (U-IMPACT)
- Ministerio de Educacion of Spain
- European Research Council (ERC)
- Region des Pays de la Loire [Marches - 278845]
- Spanish Ministerio de Ciencia e Innovacion [CTQ2011-25872, CONSOLIDER CSD2009-00038]
- Fundacion Seneca del Centro de Coordinacion de la Investigacion de la Region de Murcia [08735/PI/08]
DNA is constantly exposed to exogenous agents that randomly damage the genetic code. However, external perturbations might also be used to induce malignant cell death if the mutation processes are controlled. The present communication reports a set of parameters allowing DNA mutation through the use of intense external electric fields. This is a step towards the design of pulsed electric field therapy for genetic diseases.
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