期刊
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
卷 15, 期 38, 页码 15709-15726出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cp50415h
关键词
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资金
- EPSRC from Department of Materials, Imperial College
- Imperial College JRF
- UK EPSRC [EP/G060940/1]
- EPSRC
- Engineering and Physical Sciences Research Council [1679835, EP/K030760/1, EP/G060940/1] Funding Source: researchfish
- EPSRC [EP/G060940/1, EP/K030760/1] Funding Source: UKRI
This review focuses on metal enhanced fluorescence (MEF) and its current and future applications in biotechnology. The mechanisms of MEF are discussed in terms of the additional radiative and nonradiative decay rates caused by the close proximity of the metal. We then review the current MEF materials and structures that show promise in bioapplications. The use of electromagnetic modelling to predict fluorescent rate enhancement is then considered. We then give particular focus to the recent work carried out in the homogeneous fabrication of metal nanoparticles using colloidal lithography. It is concluded that the use of computational electromagnetic modelling alongside homogeneous fabrication techniques will lead to predictable and controllable MEF, paving the way for increased applications in biotechnology.
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