期刊
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
卷 15, 期 40, 页码 17006-17015出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cp51763b
关键词
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资金
- NIH [R01 CA170734, U19 ES019545, R01 EB016034]
- Washington Life Sciences Discovery Fund [3292512]
- Department of Bioengineering at the University of Washington
- Singapore National Research Foundation [R-279-000-323-281]
- Singapore JCO [IMRE/13-1P0909]
- Temasek Defense Systems Institute of Singapore [R279-000-305-592/422/232]
In recent years, conjugated polymers have attracted considerable attention from the imaging community as a new class of contrast agent due to their intriguing structural, chemical, and optical properties. Their size and emission wavelength tunability, brightness, photostability, and low toxicity have been demonstrated in a wide range of in vitro sensing and cellular imaging applications, and have just begun to show impact in in vivo settings. In this Perspective, we summarize recent advances in engineering conjugated polymers as imaging contrast agents, their emerging applications in molecular imaging (referred to as in vivo uses in this paper), as well as our perspectives on future research.
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