Hofmeister series reversal for lysozyme by change in pH and salt concentration: insights from electrophoretic mobility measurements

Hofmeister series reversal can occur with change in pH, or increase in salt concentration. The phenomena are a challenge for any theory of ion specific effects. Recent theoretical work predicts how a complex interplay between ionic sizes, hydration and dispersion forces explains Hofmeister series reversal. Electrophoretic mobility measurements on lysozyme suspensions reported here are consistent with the theory.