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Synthesis of Thiazolidine and Thiophene Derivatives for Evaluation as Anticancer Agents

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TAYLOR & FRANCIS LTD
DOI: 10.1080/10426500802561096

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1,2,5-Thiadiazole; thiazolidine and thiophene derivatives

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The non-isolated adducts (3a,b) were used as key intermediates to synthesize some novel thiazolidine and thiophene derivatives. Compound (4) exhibited a remarkable antitumor activity against EAC cells compared with the Doxorubicin as a positive control.

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