相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。γ-Carbolines: A novel class of cannabinoid agonists with high aqueous solubility and restricted CNS penetration
Yun-Xing Cheng et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)
5-Sulfonyl-benzimidazoles as selective CB2 agonists-Part 2
Harrie J. M. Gijsen et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)
Low brain penetrant CB1 receptor agonists for the treatment of neuropathic pain
Julia M. Adam et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)
Discovery of S-777469: An orally available CB2 agonist as an antipruritic agent
Masahide Odan et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)
Cannabinoid CB2 receptor-mediated regulation of impulsive-like behaviour in DBA/2 mice
Francisco Navarrete et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
Δ8-Tetrahydrocannabivarin prevents hepatic ischaemia/reperfusion injury by decreasing oxidative stress and inflammatory responses through cannabinoid CB2 receptors
Sandor Batkai et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
Modulation of L-α-Lysophosphatidylinositol/GPR55 Mitogen-activated Protein Kinase (MAPK) Signaling by Cannabinoids
Sharon Anavi-Goffer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Repeated morphine treatment-mediated hyperalgesia, allodynia and spinal glial activation are blocked by co-administration of a selective cannabinoid receptor type-2 agonist
Suneeta Tumati et al.
JOURNAL OF NEUROIMMUNOLOGY (2012)
Activation of Cannabinoid Receptor 2 Attenuates Leukocyte-Endothelial Cell Interactions and Blood-Brain Barrier Dysfunction under Inflammatory Conditions
Servio H. Ramirez et al.
JOURNAL OF NEUROSCIENCE (2012)
Effects of neuropeptide FF system on CB1 and CB2 receptors mediated antinociception in mice
Quan Fang et al.
NEUROPHARMACOLOGY (2012)
Intrathecal cannabilactone CB2R agonist, AM1710, controls pathological pain and restores basal cytokine levels
Jenny L. Wilkerson et al.
PAIN (2012)
Effects of a Selective Cannabinoid CB2 Agonist and Antagonist on Intravenous Nicotine Self Administration and Reinstatement of Nicotine Seeking
Islam Gamaleddin et al.
PLOS ONE (2012)
Cannabinoid receptor-2 (CB2) agonist ameliorates colitis in IL-10-/- mice by attenuating the activation of T cells and promoting their apoptosis
Udai P. Singh et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2012)
Intrathecal Administration of the Cannabinoid 2 Receptor Agonist JWH015 Can Attenuate Cancer Pain and Decrease mRNA Expression of the 2B Subunit of N-Methyl-D-Aspartic Acid
XiaoPing Gu et al.
ANESTHESIA AND ANALGESIA (2011)
Inhibition of basal and ultraviolet B-induced melanogenesis by cannabinoid CB1 receptors: a keratinocyte-dependent effect
Sofia Magina et al.
ARCHIVES OF DERMATOLOGICAL RESEARCH (2011)
CB1 and CB2 receptor agonists promote analgesia through synergy in a murine model of tumor pain
Iryna A. Khasabova et al.
BEHAVIOURAL PHARMACOLOGY (2011)
Differential Role of Anandamide and 2-Arachidonoylglycerol in Memory and Anxiety-like Responses
Arnau Busquets-Garcia et al.
BIOLOGICAL PSYCHIATRY (2011)
HIV-1 infection and alcohol abuse: Neurocognitive impairment, mechanisms of neurodegeneration and therapeutic interventions
Yuri Persidsky et al.
BRAIN BEHAVIOR AND IMMUNITY (2011)
Symptom-relieving and neuroprotective effects of the phytocannabinoid Δ9-THCV in animal models of Parkinson's disease
C. Garcia et al.
BRITISH JOURNAL OF PHARMACOLOGY (2011)
Skeletal lipidomics: regulation of bone metabolism by fatty acid amide family
Itai Bab et al.
BRITISH JOURNAL OF PHARMACOLOGY (2011)
The endocannabinoid system and cancer: therapeutic implication
Josee Guindon et al.
BRITISH JOURNAL OF PHARMACOLOGY (2011)
The endocannabinoid system as a key mediator during liver diseases: new insights and therapeutic openings
A. Mallat et al.
BRITISH JOURNAL OF PHARMACOLOGY (2011)
Prospects for cannabinoid therapies in basal ganglia disorders
Javier Fernandez-Ruiz et al.
BRITISH JOURNAL OF PHARMACOLOGY (2011)
Anti-tumoral action of cannabinoids on hepatocellular carcinoma: role of AMPK-dependent activation of autophagy
D. Vara et al.
CELL DEATH AND DIFFERENTIATION (2011)
Cannabinoid-Opioid Interaction in Chronic Pain
D. I. Abrams et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2011)
G-protein coupled receptors regulating cough
Sarah A. Maher et al.
CURRENT OPINION IN PHARMACOLOGY (2011)
Protective Role of Cannabinoid Receptor Type 2 in a Mouse Model of Diabetic Nephropathy
Federica Barutta et al.
DIABETES (2011)
Recent advances in the understanding of the role of the endocannabinoid system in liver diseases
Li Huang et al.
DIGESTIVE AND LIVER DISEASE (2011)
Update on the endocannabinoid system as an anticancer target
Anna Maria Malfitano et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2011)
Cannabinoid CB2 Receptors Protect Against Alcoholic Liver Disease by Regulating Kupffer Cell Polarization in Mice
Alexandre Louvet et al.
HEPATOLOGY (2011)
Unraveling the complexities of cannabinoid receptor 2 (CB2) immune regulation in health and disease
Sreemanti Basu et al.
IMMUNOLOGIC RESEARCH (2011)
Discovery and Optimization of 1-(4-(Pyridin-2-yl)benzyl)imidazolidine-2,4-dione Derivatives As a Novel Class of Selective Cannabinoid CB2 Receptor Agonists
Mario van der Stelt et al.
JOURNAL OF MEDICINAL CHEMISTRY (2011)
Atheroprotection via cannabinoid receptor-2 is mediated by circulating and vascular cells in vivo
Friedrich Felix Hoyer et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2011)
Modulation of Inflammatory Responses by a Cannabinoid-2-Selective Agonist after Spinal Cord Injury
Sabina Adhikary et al.
JOURNAL OF NEUROTRAUMA (2011)
Acute Effects of a Selective Cannabinoid-2 Receptor Agonist on Neuroinflammation in a Model of Traumatic Brain Injury
Melanie B. Elliott et al.
JOURNAL OF NEUROTRAUMA (2011)
Nonpsychotropic Cannabinoids, Abnormal Cannabidiol and Canabigerol-Dimethyl Heptyl, Act at Novel Cannabinoid Receptors to Reduce Intraocular Pressure
Anna-Maria Szczesniak et al.
JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS (2011)
Therapeutic Potential of Cannabinoids in the Treatment of Neuroinflammation Associated with Parkinsons Disease
J. P. Little et al.
MINI-REVIEWS IN MEDICINAL CHEMISTRY (2011)
A Combined Preclinical Therapy of Cannabinoids and Temozolomide against Glioma
Sofia Torres et al.
MOLECULAR CANCER THERAPEUTICS (2011)
Brain cannabinoid CB2 receptors modulate cocaine's actions in mice
Zheng-Xiong Xi et al.
NATURE NEUROSCIENCE (2011)
Antinociceptive effect of intrathecal cannabinoid receptor agonist WIN 55,212-2 in a rat bone tumor pain model
Jin Hua Cui et al.
NEUROSCIENCE LETTERS (2011)
Self-medication of a cannabinoid CB2 agonist in an animal model of neuropathic pain
Tannia Gutierrez et al.
PAIN (2011)
Cannabinoid Agonists Inhibit Neuropathic Pain Induced by Brachial Plexus Avulsion in Mice by Affecting Glial Cells and MAP Kinases
Ana F. Paszcuk et al.
PLOS ONE (2011)
Crosstalk between Chemokine Receptor CXCR4 and Cannabinoid Receptor CB2 in Modulating Breast Cancer Growth and Invasion
Mohd W. Nasser et al.
PLOS ONE (2011)
Increasing 2-arachidonoyl glycerol signaling in the periphery attenuates mechanical hyperalgesia in a model of bone cancer pain
Iryna A. Khasabova et al.
PHARMACOLOGICAL RESEARCH (2011)
Synthetic cannabinoid WIN 55,212-2 mesylate enhances the protective action of four classical antiepileptic drugs against maximal electroshock-induced seizures in mice
Jarogniew J. Luszczki et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2011)
Pharmacological characterization of AM1710, a putative cannabinoid CB2 agonist from the cannabilactone class: Antinociception without central nervous system side-effects
Elizabeth J. Rahn et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2011)
Centrally mediated antinociceptive effects of cannabinoid receptor ligands in rat models of nociception
Aldric Hama et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2011)
Fatty acid amide hydrolase blockade attenuates the development of collagen-induced arthritis and related thermal hyperalgesia in mice
Steven G. Kinsey et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2011)
Effects of WIN 55,212-2 mesylate (a synthetic cannabinoid) on the protective action of clonazepam, ethosuximide, phenobarbital and valproate against pentylenetetrazole-induced clonic seizures in mice
Jarogniew J. Luszczki et al.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2011)
LOW-VOLUME BINARY DRUG THERAPY FOR THE TREATMENT OF HYPOVOLEMIA
Himanshu Bhattacharjee et al.
SHOCK (2011)
Gemcitabine/cannabinoid combination triggers autophagy in pancreatic cancer cells through a ROS-mediated mechanism
M. Donadelli et al.
CELL DEATH & DISEASE (2011)
Inactivation of the Cannabinoid Receptor CB1 Prevents Leukocyte Infiltration and Experimental Fibrosis
Sieglinde Marquart et al.
ARTHRITIS AND RHEUMATISM (2010)
The plant cannabinoid Δ9-tetrahydrocannabivarin can decrease signs of inflammation and inflammatory pain in mice
Daniele Bolognini et al.
BRITISH JOURNAL OF PHARMACOLOGY (2010)
The antinociceptive effect of acetylsalicylic acid is differently affected by a CB1 agonist or antagonist and involves the serotonergic system in rats
Valentina Ruggieri et al.
LIFE SCIENCES (2010)
Attenuation of morphine antinociceptive tolerance by a CB1 receptor agonist and an NMDA receptor antagonist: Interactive effects
Bradford D. Fischer et al.
NEUROPHARMACOLOGY (2010)
A peripherally restricted cannabinoid receptor agonist produces robust anti-nociceptive effects in rodent models of inflammatory and neuropathic pain
Xiao Hong Yu et al.
PAIN (2010)
Effect of arachidonyl-2′-chloroethylamide, a selective cannabinoid CB1 receptor agonist, on the protective action of the various antiepileptic drugs in the mouse maximal electroshock-induced seizure model
Jarogniew J. Luszczki et al.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2010)
Cannabinoids and the skeleton: From marijuana to reversal of bone loss
Itai Bab et al.
ANNALS OF MEDICINE (2009)
Emerging strategies for exploiting cannabinoid receptor agonists as medicines
Roger G. Pertwee
BRITISH JOURNAL OF PHARMACOLOGY (2009)
The future of endocannabinoid-oriented clinical research after CB1 antagonists
Bernard Le Foll et al.
PSYCHOPHARMACOLOGY (2009)
Interaction of the cannabinoid and opioid systems in the modulation of nociception
Sandra P. Welch
INTERNATIONAL REVIEW OF PSYCHIATRY (2009)
The cannabinoid receptor agonist, WIN 55, 212-2, attenuates tumor-evoked hyperalgesia through peripheral mechanisms
Carl Potenzieri et al.
BRAIN RESEARCH (2008)
CB2 receptors as new therapeutic targets for liver diseases
S. Lotersztajn et al.
BRITISH JOURNAL OF PHARMACOLOGY (2008)
Cannabinoid CB2 receptors: a therapeutic target for the treatment of inflammatory and neuropathic pain
J. Guindon et al.
BRITISH JOURNAL OF PHARMACOLOGY (2008)
Direct suppression of autoreactive lymphocytes in the central nervous system via the CB2 receptor
B. N. Dittel
BRITISH JOURNAL OF PHARMACOLOGY (2008)
The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Delta(9)-tetrahydrocannabinol, cannabidiol and Delta(9)-tetrahydrocannabivarin
R. G. Pertwee
BRITISH JOURNAL OF PHARMACOLOGY (2008)
Endocannabinoids and cannabinoid receptors in ischaemia-reperfusion injury and preconditioning
P. Pacher et al.
BRITISH JOURNAL OF PHARMACOLOGY (2008)
Cannabinoid CB2 receptors in the gastrointestinal tract: a regulatory system in states of inflammation
K. L. Wright et al.
BRITISH JOURNAL OF PHARMACOLOGY (2008)
The cannabinoid anticonvulsant effect on pentylenetetrazole-induced seizure is potentiated by ultra-low dose naltrexone in mice
Arash Bahremand et al.
EPILEPSY RESEARCH (2008)
Involvement of central cannabinoid CB2 receptor in reducing mechanical allodynia in a mouse model of neuropathic pain
Wataru Yamamoto et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2008)
Emerging role of cannabinoids in gastrointestinal and liver diseases: basic and clinical aspects
A. A. Izzo et al.
GUT (2008)
Evaluation of interactions between cannabinoid compounds and diazepam in electroshock-induced seizure model in mice
Nima Naderi et al.
JOURNAL OF NEURAL TRANSMISSION (2008)
Efficacy of dronabinol as an adjuvant treatment for chronic pain patients on opioid therapy
Sanjeet Narang et al.
JOURNAL OF PAIN (2008)
Modulation of the balance between cannabinoid CB1 and CB2 receptor activation during cerebral ischemic/reperfusion injury
M. Zhang et al.
NEUROSCIENCE (2008)
Interaction between cannabinoid compounds and diazepam on anxiety-like behaviour of mice
Nima Naderi et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2008)
Interactions between Δ9-tetrahydrocannabinol and μ opioid receptor agonists in rhesus monkeys:: discrimination and antinociception
Jun-Xu Li et al.
PSYCHOPHARMACOLOGY (2008)
Control of spasticity in a multiple sclerosis model is mediated by CB1, not CB2, cannabinoid receptors
G. Pryce et al.
BRITISH JOURNAL OF PHARMACOLOGY (2007)
Cannabinoid-induced tolerance is associated with a CB1 receptor G protein coupling switch that is prevented by ultra-low dose rimonabant
Jay J. Paquette et al.
BEHAVIOURAL PHARMACOLOGY (2007)
Ultra-low dose cannabinoid antagonist AM251 enhances cannabinoid anticonvulsant effects in the pentylenetetrazole-induced seizure in mice
Shervin Gholizadeh et al.
NEUROPHARMACOLOGY (2007)
Blockade of central cyclooxygenase (COX) pathways enhances the cannabinold-induced antinociceptive effects on inflammatory temporomandibular joint (TMJ) nociception
Dong K. Ahn et al.
PAIN (2007)
Low dose combination of morphine and Δ9-tetrahydrocannabinol circumvents antinociceptive tolerance and apparent
Paul A. Smith et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2007)
Naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methanone:: A potent, orally bioavailable human CB1/CB2 dual agonist with antihyperalgesic properties and restricted central nervous system penetration
Edward K. Dziadulewicz et al.
JOURNAL OF MEDICINAL CHEMISTRY (2007)
Cannabinoids and multiple sclerosis
Roger G. Pertwee
MOLECULAR NEUROBIOLOGY (2007)
Synergy between Δ9-tetrahydrocannabinol and morphine in the arthritic rat
Melinda L. Cox et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2007)
Cannabinoid CB2 receptor activation decreases cerebral infarction in a mouse focal ischemia/reperfusion model
Ming Zhang et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2007)
Spinal cannabinoid receptor type 2 activation reduces hypersensitivity and spinal cord glial activation after paw incision
Alfonso Romero-Sandoval et al.
ANESTHESIOLOGY (2007)
The CB2 cannabinoid agonist AM-1241 prolongs survival in a transgenic mouse model of amyotrophic lateral sclerosis when initiated at symptom onset
Jennifer L. Shoemaker et al.
JOURNAL OF NEUROCHEMISTRY (2007)
Antinociceptive synergy between the cannabinoid receptor agonist WIN 55,212-2 and bupivacaine in the rat formalin test
Sinyoung Kang et al.
ANESTHESIA AND ANALGESIA (2007)
Adolescent cannabis exposure alters opiate intake and opioid limbic neuronal populations in adult rats
Maria Ellgren et al.
NEUROPSYCHOPHARMACOLOGY (2007)
5-HT1A receptors are involved in the anxiolytic effect of Δ9-tetrahydrocannabinol and AM 404, the anandamide transport inhibitor, in Sprague-Dawley rats
Daniela Braida et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2007)
Cannabinoid receptors as new targets of antifibrosing strategies during chronic liver diseases
Ariane Mallat et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2007)
The role of the cannabinoid CB2 receptor in pain transmission and therapeutic potential of small molecule CB2 receptor agonists
G. T. Whiteside et al.
CURRENT MEDICINAL CHEMISTRY (2007)
AM1241, a cannabinoid CB2 receptor selective compound, delays disease progression in a mouse model of amyotrophic lateral sclerosis
Kathline Kim et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2006)
Time course of the enhancement and restoration of the analgesic efficacy of codeine and morphine by Δ9-tetrahydrocannabinol
I. Jovan Williams et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2006)
Δ9-tetrahydrocannabinol and the opioid receptor agonist piritramide do not act synergistically in postoperative pain
W. Seeling et al.
ANAESTHESIST (2006)
CB2 receptor-mediated antihyperalgesia: possible direct involvement of neural mechanisms
M Beltramo et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2006)
Local interactions between anandamide, an endocannabinoid, and ibuprofen, a nonsteroidal anti-inflammatory drug, in acute and inflammatory pain
J Guindon et al.
PAIN (2006)
The additive antinociceptive interaction between WIN 55,212-2, a cannabinoid agonist, and ketorolac
A Ulugöl et al.
ANESTHESIA AND ANALGESIA (2006)
Role of the cannabinoid system in the effects induced by nicotine on anxiety-like behaviour in mice
GN Balerio et al.
PSYCHOPHARMACOLOGY (2006)
Synergistic affective analgesic interaction between delta-9-tetrahydrocannabinol and morphine
JD Roberts et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2006)
Enhancement of transdermal fentanyl and buprenorphine antinociception by transdermal Δ9-tetrahydrocannabinol
DL Cichewicz et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2005)
Low dose oral cannabinoid therapy reduces progression of atherosclerosis in mice
S Steffens et al.
NATURE (2005)
Synergistic and additive interactions of the cannabinoid agonist CP55,940 with μ opioid receptor and α2-adrenoceptor agonists in acute pain models in mice
SM Tham et al.
BRITISH JOURNAL OF PHARMACOLOGY (2005)
The therapeutic potential of drugs that target cannabinoid receptors or modulate the tissue levels or actions of endocannabinoids
RG Pertwee
AAPS JOURNAL (2005)
Effects of coadministration of cannabinoids and morphine on nociceptive behaviour, brain monoamines and HPA axis activity in a rat model of persistent pain
DP Finn et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2004)
Synergistic interactions between cannabinoid and opioid analgesics
DL Cichewicz
LIFE SCIENCES (2004)
Cannabinoid agonist-induced sensitisation to morphine place preference in mice
C Manzanedo et al.
NEUROREPORT (2004)
Haloperidol, but not clozapine, produces dramatic catalepsy in Δ9THC-treated rats:: possible clinical implications
G Marchese et al.
BRITISH JOURNAL OF PHARMACOLOGY (2003)
Pharmacologic interaction between cannabinoid and either clonidine or neostigmine in the rat formalin test
MH Yoon et al.
ANESTHESIOLOGY (2003)
Topical cannabinoid enhances topical morphine antinociception
O Yesilyurt et al.
PAIN (2003)
The analgesic effect of oral delta-9-tetrahydrocannabinol (THC), morphine, and a THC-morphine combination in healthy subjects under experimental pain conditions
M Naef et al.
PAIN (2003)
Topical cannabinoid antinociception: synergy with spinal sites
A Dogrul et al.
PAIN (2003)
Histamine induced responses are attenuated by a cannabinoid receptor agonist in human skin
M Dvorak et al.
INFLAMMATION RESEARCH (2003)
Cannabinoid agonists attenuate capsaicin-induced responses in human skin
R Rukwied et al.
PAIN (2003)
Antinociceptive synergy between Δ9-tetrahydrocannabinol and opioids after oral administration
DL Cichewicz et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2003)
Behavioural and biochemical evidence for interactions between Delta 9-tetrahydrocannabinol and nicotine
E Valjent et al.
BRITISH JOURNAL OF PHARMACOLOGY (2002)