期刊
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES
卷 368, 期 1912, 页码 561-583出版社
ROYAL SOC
DOI: 10.1098/rsta.2009.0248
关键词
multi-scale modelling; heat and mass transfer; cryopreservation
资金
- NIH [R21 (EB007707), R01 (AI081534)]
- Dankook University
Cells and tissues undergo complex physical processes during cryopreservation. Understanding the underlying physical phenomena is critical to improve current cryopreservation methods and to develop new techniques. Here, we describe multi-scale approaches for modelling cell and tissue cryopreservation including heat transfer at macroscale level, crystallization, cell volume change and mass transport across cell membranes at microscale level. These multi-scale approaches allow us to study cell and tissue cryopreservation.
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