相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Origins and functional impact of copy number variation in the human genome
Donald F. Conrad et al.
NATURE (2010)
KRAS Mutation Testing in Colorectal Cancer
Thomas P. Plesec et al.
ADVANCES IN ANATOMIC PATHOLOGY (2009)
Novel pharmacogenetic markers for treatment outcome in azathioprine-treated inflammatory bowel disease
M. A. Smith et al.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2009)
KRAS Mutational Status as a Predictor of Epidermal Growth Factor Receptor Inhibitor Efficacy in Colorectal Cancer
Roy D. Baynes et al.
AMERICAN JOURNAL OF THERAPEUTICS (2009)
Epidermal growth factor receptor inhibitors in cancer treatment: advances, challenges and opportunities
Helmout Modjtahedi et al.
ANTI-CANCER DRUGS (2009)
Mammalian epoxide hydrolases in xenobiotic metabolism and signalling
Martina Decker et al.
ARCHIVES OF TOXICOLOGY (2009)
Targeting DNA repair pathways: A novel approach to reduce cancer therapeutic resistance
Yongjian Zhu et al.
CANCER TREATMENT REVIEWS (2009)
Metallothioneins and Platinum(II) Anti-Tumor Compounds
Markus Knipp
CURRENT MEDICINAL CHEMISTRY (2009)
A genome-wide association study of acenocoumarol maintenance dosage
Martina Teichert et al.
HUMAN MOLECULAR GENETICS (2009)
Genome-wide Interrogation of Germline Genetic Variation Associated With Treatment Response in Childhood Acute Lymphoblastic Leukemia
Jun J. Yang et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2009)
Association of Cytochrome P450 2C19 Genotype With the Antiplatelet Effect and Clinical Efficacy of Clopidogrel Therapy
Alan R. Shuldiner et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2009)
Genome-Wide Association Study of Determinants of Anti-Cyclic Citrullinated Peptide Antibody Titer in Adults with Rheumatoid Arthritis
Jing Cui et al.
MOLECULAR MEDICINE (2009)
Whole genome association study identifies polymorphisms associated with QT prolongation during iloperidone treatment of schizophrenia
S. Volpi et al.
MOLECULAR PSYCHIATRY (2009)
Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance
Dongliang Ge et al.
NATURE (2009)
HLA-B☆5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin
Ann K. Daly et al.
NATURE GENETICS (2009)
IL28B is associated with response to chronic hepatitis C interferon-α and ribavirin therapy
Vijayaprakash Suppiah et al.
NATURE GENETICS (2009)
Genome-wide association of IL28B with response to pegylated interferon-α and ribavirin therapy for chronic hepatitis C
Yasuhito Tanaka et al.
NATURE GENETICS (2009)
Cytochrome P-450 Polymorphisms and Response to Clopidogrel.
Jessica L. Mega et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
The impact of microRNAs and alternative splicing in pharmacogenomics
F. Passetti et al.
PHARMACOGENOMICS JOURNAL (2009)
A Genome-Wide Association Study Confirms VKORC1, CYP2C9, and CYP4F2 as Principal Genetic Determinants of Warfarin Dose
Fumihiko Takeuchi et al.
PLOS GENETICS (2009)
Glutathione peroxidase 1-deficient mice are more susceptible to doxorubicin-induced cardiotoxicity
Jinping Gao et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2008)
CYP4F2 genetic variant alters required warfarin dose
Michael D. Caldwell et al.
BLOOD (2008)
A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose
Gregory M. Cooper et al.
BLOOD (2008)
Bisphosphonate-related osteonecrosis of the jaw is associated with polymorphisms of the cytochrome P450CYP2C8 in multiple myeloma:: a genome-wide single nucleotide polymorphism analysis
Maria E. Sarasquete et al.
BLOOD (2008)
IMPDH activity in thiopurine-treated patients with inflammatory bowel disease - relation to TPMT activity and metabolite concentrations
Sofie Haglund et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2008)
Cellular basis of drug-induced torsades de pointes
D. M. Roden
BRITISH JOURNAL OF PHARMACOLOGY (2008)
Linking antibody Fc domain to endostatin significantly improves endostatin half-life and efficacy
Tong-Young Lee et al.
CLINICAL CANCER RESEARCH (2008)
Peroxidase-mediated bioactivation of hydroxylated metabolites of carbamazepine and phenytoin
Wei Lu et al.
DRUG METABOLISM AND DISPOSITION (2008)
THE ALDO-KETO REDUCTASE SUPERFAMILY AND ITS ROLE IN DRUG METABOLISM AND DETOXIFICATION
Oleg A. Barski et al.
DRUG METABOLISM REVIEWS (2008)
Evaluation of coverage variation of SNP chips for genome-wide association studies
Mingyao Li et al.
EUROPEAN JOURNAL OF HUMAN GENETICS (2008)
Modifications of human carboxylesterase for improved prodrug activation
Jason M. Hatfield et al.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2008)
Genome-wide association scan identifies candidate polymorphisms associated with differential response to anti-TNF treatment in rheumatoid arthritis
Chunyu Liu et al.
MOLECULAR MEDICINE (2008)
Impact of lipoproteins on the biological activity and disposition of hydrophobic drugs: implications for drug discovery
Kishor M. Wasan et al.
NATURE REVIEWS DRUG DISCOVERY (2008)
SLCO1B1Variants and Statin-Induced Myopathy — A Genomewide Study
NEW ENGLAND JOURNAL OF MEDICINE (2008)
The role of metallothionein in oncogenesis and cancer prognosis
Mie Ø. Pedersen et al.
PROGRESS IN HISTOCHEMISTRY AND CYTOCHEMISTRY (2008)
Overexpression of cytochrome P450NADPH reductase sensitises MDA 231 breast carcinoma cells to 5-fluorouracil: Possible mechanisms involved
Vanesa G. Martinez et al.
TOXICOLOGY IN VITRO (2008)
Genome-wide pharmacogenetic investigation of a hepatic adverse event without clinical signs of immunopathology suggests an underlying immune pathogenesis
A. Kindmark et al.
PHARMACOGENOMICS JOURNAL (2008)
DrugBank: a knowledgebase for drugs, drug actions and drug targets
David S. Wishart et al.
NUCLEIC ACIDS RESEARCH (2008)
miRBase: tools for microRNA genomics
Sam Griffiths-Jones et al.
NUCLEIC ACIDS RESEARCH (2008)
The emerging role of pharmacogenomics in Biologics
E. Lacana et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2007)
The non-ABC drug transporter RLIP76 (RALBP-1) plays a major role in the mechanisms of drug resistance
Yogesh C. Awasthi et al.
CURRENT DRUG METABOLISM (2007)
Understanding ribonucleotide reductase inactivation by gemcitabine
Nuno M. F. S. A. Cerqueira et al.
CHEMISTRY-A EUROPEAN JOURNAL (2007)
The impact of cytochrome P450 2D6 metabolism in women receiving adjuvant tamoxifen
Matthew P. Goetz et al.
BREAST CANCER RESEARCH AND TREATMENT (2007)
Genetic variability in the cytochrome P450-paraoxonase 1 (PON1) pathway for detoxication of organophosphorus compounds
Clement E. Furlong
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2007)
Amino acid conjugation: contribution to the metabolism and toxicity of xenobiotic carboxylic acids
Kathleen M. Knights et al.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2007)
Cellular functions of vaults and their involvement in multidrug resistance
E. Steiner et al.
CURRENT DRUG TARGETS (2006)
Translocator protein (18 kDa):: new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function
Vassilios Papadopoulos et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2006)
The role of amine oxidases in xenobiotic metabolism
Bin Gong et al.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2006)
Valproate-induced hyperammonemic encephalopathy
N. Segura-Bruna et al.
ACTA NEUROLOGICA SCANDINAVICA (2006)
Drug transporters in pharmacokinetics
E Petzinger et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2006)
Inhibition of five lipoxygenase activating protein (FLAP) by MK-886 decreases atherosclerosis in apoE/LDLR-double knockout mice
J Jawien et al.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION (2006)
Clinical course of patients with non-small cell lung cancer and epidermal growth factor receptor exon 19 and exon 21 mutations treated with gefitinib or erlotinib
GJ Riely et al.
CLINICAL CANCER RESEARCH (2006)
G proteins in drug screening: From analysis of receptor-G protein specificity to manipulation of GPCR-mediated signalling pathways
Evi Kostenis
CURRENT PHARMACEUTICAL DESIGN (2006)
Equal proportion of adult male and female homozygous for the 677C→T mutation in the methylenetetrahydrofolate reductase polymorphism
CAM Anderson et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2005)
Role of human aldehyde dehydrogenases in endobiotic and xenobiotic metabolism
V Vasiliou et al.
DRUG METABOLISM REVIEWS (2004)
Drug methylation in cancer therapy: lessons from the TPMT polymorphism
E Krynetski et al.
ONCOGENE (2003)
N-oxidation of drugs associated with idiosyncratic drug reactions
J Uetrecht
DRUG METABOLISM REVIEWS (2002)
PharmGKB: The Pharmacogenetics Knowledge Base
M Hewett et al.
NUCLEIC ACIDS RESEARCH (2002)