相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Effects of non-ionic surfactants on in vitro triglyceride digestion and their susceptibility to digestion by pancreatic enzymes
Anne Christiansen et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2010)
A comparative kinetic study on human pancreatic and Thermomyces lanuginosa lipases: Inhibitory effects of tetrahydrolipstatin in the presence of lipid substrates
Ali Tiss et al.
JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC (2010)
Weight Loss, HbA(1c) Reduction, and Tolerability of Cetilistat in a Randomized, Placebo-controlled Phase 2 Trial in Obese Diabetics: Comparison With Orlistat (Xenical)
Peter Kopelman et al.
OBESITY (2010)
The role of lipid and carbohydrate digestive enzyme inhibitors in the management of obesity: a review of current and emerging therapeutic agents
Sonia Tucci
Diabetes Metabolic Syndrome and Obesity-Targets and Therapy (2010)
Lid Opening and Unfolding in Human Pancreatic Lipase at Low pH Revealed by Site-Directed Spin Labeling EPR and FTIR Spectroscopy
Sebastien Ranaldi et al.
BIOCHEMISTRY (2009)
Reduction of dietary fat absorption by the novel gastrointestinal lipase inhibitor cetilistat in healthy volunteers
Andrew Bryson et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2009)
Inhibition of human pancreatic lipase by tetrahydrolipstatin: Further kinetic studies showing its reversibility
Ali Tiss et al.
JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC (2009)
Inhibition of Fatty Acid Synthase by Orlistat Accelerates Gastric Tumor Cell Apoptosis in Culture and Increases Survival Rates in Gastric Tumor Bearing Mice In Vivo
Shawn Dowling et al.
LIPIDS (2009)
In Vitro Gastrointestinal Lipolysis of Four Formulations of Piroxicam and Cinnarizine with the Self Emulsifying Excipients Labrasol® and Gelucire® 44/14
Sylvie Fernandez et al.
PHARMACEUTICAL RESEARCH (2009)
Approaches to the pharmacological treatment of obesity
Victoria Salem et al.
Expert Review of Clinical Pharmacology (2009)
Formulation of lipid-based delivery systems for oral administration: Materials, methods and strategies
Colin W. Pouton et al.
ADVANCED DRUG DELIVERY REVIEWS (2008)
Lipolytic enzymes in Mycobacterium tuberculosis
K. Cotes et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2008)
Lipolysis of the semi-solid self-emulsifying excipient Gelucire® 44/14 by digestive lipases
Sylvie Fernandez et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2008)
Cetilistat (ATL-962), a novel pancreatic lipase inhibitor, ameliorates body weight gain and improves lipid profiles in rats
Y. Yamada et al.
HORMONE AND METABOLIC RESEARCH (2008)
Functional role of the PE domain and immunogenicity of the Mycobacterium tuberculosis triacylglycerol hydrolase LipY
Kanhu C. Mishra et al.
INFECTION AND IMMUNITY (2008)
A comparative study on two fungal lipases from Thermomyces lanuginosus and Yarrowia lipolytica shows the combined effects of detergents and pH on lipase adsorption and activity
Ahmed Aloulou et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2007)
Comparative study on digestive lipase activities on the self emulsifying excipient Labrasol®, medium chain glycerides and PEG esters
Sylvie Fernandez et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2007)
Cetilistat (ATL-962), a novel lipase inhibitor: a 12-week randomized, placebo-controlled study of weight reduction in obese patients
P. Kopelman et al.
INTERNATIONAL JOURNAL OF OBESITY (2007)
Probing the opening of the pancreatic lipase lid using site-directed spin labeling and EPR spectroscopy
Valerie Belle et al.
BIOCHEMISTRY (2007)
Use of an inhibitor to identify members of the hormone-sensitive lipase family
Yassine Ben Ali et al.
BIOCHEMISTRY (2006)
How gastric lipase, an interfacial enzyme with a Ser-His-Asp catalytic triad, acts optimally at acidic pH
H Chahinian et al.
BIOCHEMISTRY (2006)
Exploring the specific features of interfacial enzymology based on lipase studies
Ahmed Aloulou et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2006)
Activation, inhibition, and destabilization of thermomyces lanuginosus lipase by detergents
JE Mogensen et al.
BIOCHEMISTRY (2005)
Self-emulsifying drug delivery systems (SEDDS) for improved oral delivery of lipophilic drugs
RN Gursoy et al.
BIOMEDICINE & PHARMACOTHERAPY (2004)
Might the kinetic behavior of hormone-sensitive lipase reflect the absence of the lid domain?
Y Ben Ali et al.
BIOCHEMISTRY (2004)
Inhibition of dog and human gastric lipases by enantiomeric phosphonate inhibitors:: A structure-activity study
N Miled et al.
BIOCHEMISTRY (2003)
Transfer of orlistat through oil-water interfaces
A Tiss et al.
CHEMISTRY AND PHYSICS OF LIPIDS (2002)
Protein unfolding in detergents: Effect of micelle structure, ionic strength, pH, and temperature
DE Otzen
BIOPHYSICAL JOURNAL (2002)
Orlistat: its current status as an anti-obesity drug
A Ballinger et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2002)
Burst-phase expansion of native protein prior to global unfolding in SDS
DE Otzen et al.
JOURNAL OF MOLECULAR BIOLOGY (2002)
Crystal structure of the open form of dog gastric lipase in complex with a phosphonate inhibitor
A Roussel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Effects of gum Arabic on lipase interfacial binding and activity
A Tiss et al.
ANALYTICAL BIOCHEMISTRY (2001)
On relationships between molecular structure, interaction and surface behavior in mixture: small-molecule surfactant plus protein
AS Antipova et al.
COLLOIDS AND SURFACES B-BIOINTERFACES (2001)
Surface behaviour of bile salts and tetrahydrolipstatin at air/water and oil/water interfaces
A Tiss et al.
CHEMISTRY AND PHYSICS OF LIPIDS (2001)
The closed/open model for lipase activation.: Addressing intermediate active forms of fungal enzymes by trapping of conformers in water-restricted environments
H González-Navarro et al.
BIOCHEMISTRY (2001)
Structural origins of the interfacial activation in Thermomyces (Humicola) lanuginosa lipase
AM Brzozowski et al.
BIOCHEMISTRY (2000)
Drug-like properties and the causes of poor solubility and poor permeability
CA Lipinski
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS (2000)
Dynamics of protein and mixed protein/surfactant adsorption layers at the water/fluid interface
R Miller et al.
ADVANCES IN COLLOID AND INTERFACE SCIENCE (2000)