期刊
PHARMACEUTICAL CHEMISTRY JOURNAL
卷 47, 期 12, 页码 655-659出版社
SPRINGER
DOI: 10.1007/s11094-014-1026-6
关键词
pyrano[3,4-c]pyridines; thieno[3,2-d]pyrimidines; furo[3,2-d]pyrimidines; cyclization; amino derivatives; neurotropic activity
New derivatives of pyrano[4aEuro(3),3aEuro(3):4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidines based on 3-chloro derivatives of pyrano[3,4-c]pyridines and pyrano[4aEuro(3),3aEuro(3):4',5']pyrido[3',2':4,5]furo[3,2-d]pyrimidines based on previously prepared 8-chloro derivatives were synthesized. Studies of the biological activity of the synthesized compounds showed that several of them exhibited neurotropic properties.
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