Rapid vacuolar sequestration: the horseweed glyphosate resistance mechanism

BACKGROUND: Glyphosate-resistant (GR) weed species are now found with increasing frequency and threaten the critically important GR weed management system. RESULTS: The reported P-31 NMR experiments on glyphosate-sensitive (5) and glyphosate-resistant (R) horseweed, Conyza canadensis (L.) Cronq., show significantly more accumulation of glyphosate within the R biotype vacuole. CONCLUSIONS: Selective sequestration of glyphosate into the vacuole confers the observed horseweed resistance to glyphosate. This observation represents the first clear evidence for the glyphosate resistance mechanism in C. canadensis. (C) 2010 Society of Chemical Industry