期刊
PEPTIDES
卷 30, 期 11, 页码 1969-1972出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.peptides.2009.07.016
关键词
Hypothalamus; Neurogenesis
Although a great deal is published on the MCH neurons, very few works were devoted to the study of their development. However, existing literature points out two important traits: first, these neurons differentiate a MCH phenotype very early in all species studied so far, which might suggest a role for the MCH peptide during development; second, in the rat, birth date greatly influence the phenotype of MCH neurons. At least two sub-populations were described on the basis of their chemical phenotype, projection pattern and birth date. The understanding of processes involved in the differentiation of these sub-populations may help understand the medio-lateral differentiation of the tuberal hypothalamus. (c) 2009 Elsevier Inc. All rights reserved.
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