期刊
TRENDS IN MICROBIOLOGY
卷 23, 期 12, 页码 775-788出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.tim.2015.09.002
关键词
-
资金
- Human Frontiers in Science Program [RGP0061/2013]
- Deutsche Forschungsgemeinschaft [MA3898]
- National Science Foundation [DMR1411329]
The bacterial type IV pilus (T4P) is a versatile molecular machine with a broad range of functions. Recent advances revealed that the molecular components and the biophysical properties of the machine are well conserved among phylogenetically distant bacterial species. However, its functions are diverse, and include adhesion, motility, and horizontal gene transfer. This review focusses on the role of T4P in surface motility and bacterial interactions. Different species have evolved distinct mechanisms for intracellular coordination of multiple pili and of pill with other motility machines, ranging from physical coordination to biochemical clocks. Coordinated behavior between multiple bacteria on a surface is achieved by active manipulation of surfaces and modulation of pilus-pilus interactions. An emerging picture is that the T4P actively senses and responds to environmental conditions.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据