期刊
TRENDS IN ENDOCRINOLOGY AND METABOLISM
卷 26, 期 10, 页码 511-512出版社
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tem.2015.07.009
关键词
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Short-chain fatty acids (SCFAs) are released upon fermentation of dietary fiber by gut bacteria. G protein-coupled receptor 43 (GPR43), a key receptor for SCFAs, is expressed on cell types important for immunity and metabolism. GPR43 modulates both inflammatory and metabolic processes, and is crucial for understanding the pathogenesis of 'Western lifestyle' diseases.
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