期刊
TRENDS IN COGNITIVE SCIENCES
卷 19, 期 9, 页码 534-543出版社
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tics.2015.07.004
关键词
parietal cortex; memory; familiarity; encoding; retrieval; functional networks
资金
- National Science Foundation [DGE-1143954]
- Dart NeuroScience LLC
- McDonnell Center for Systems Neuroscience at Washington University in St Louis
The manner by which the human brain learns and recognizes stimuli is a matter of ongoing investigation. Through examination of meta-analyses of task-based functional MRI and resting state functional connectivity MRI, we identified a novel network strongly related to learning and memory. Activity within this network at encoding predicts subsequent item memory, and at retrieval differs for recognized and unrecognized items. The direction of activity flips as a function of recent history: from deactivation for novel stimuli to activation for stimuli that are familiar due to recent exposure. We term this network the 'parietal memory network' (PMN) to reflect its broad involvement in human memory processing. We provide a preliminary framework for understanding the key functional properties of the network.
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