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X. Wang et al.
ONCOGENE (2012)
Polycomb genes expression as a predictor of poor clinical outcome in children with medulloblastoma
Magdalena Zakrzewska et al.
CHILDS NERVOUS SYSTEM (2011)
Integrative Genomic Analysis of Medulloblastoma Identifies a Molecular Subgroup That Drives Poor Clinical Outcome
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JOURNAL OF CLINICAL ONCOLOGY (2011)
Medulloblastoma Comprises Four Distinct Molecular Variants
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JOURNAL OF CLINICAL ONCOLOGY (2011)
Identification and Characterization of KCASH2 and KCASH3, 2 Novel Cullin3 Adaptors Suppressing Histone Deacetylase and Hedgehog Activity in Medulloblastoma
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Childhood medulloblastoma: novel approaches to the classification of a heterogeneous disease
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Atoh1 Inhibits Neuronal Differentiation and Collaborates with Gli1 to Generate Medulloblastoma-Initiating Cells
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CANCER RESEARCH (2010)
Hedgehog controls neural stem cells through p53-independent regulation of Nanog
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EMBO JOURNAL (2010)
Subtypes of medulloblastoma have distinct developmental origins
Paul Gibson et al.
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Histone deacetylase and Cullin3-RENKCTD11 ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation
Gianluca Canettieri et al.
NATURE CELL BIOLOGY (2010)
Bmi1 is essential in Twist1-induced epithelial-mesenchymal transition
Muh-Hwa Yang et al.
NATURE CELL BIOLOGY (2010)
Canonical Notch signaling is not required for the growth of Hedgehog pathway-induced medulloblastoma
E. Julian et al.
ONCOGENE (2010)
Cerebellar stem cells act as medulloblastoma-initiating cells in a mouse model and a neural stem cell signature characterizes a subset of human medulloblastomas
R. Sutter et al.
ONCOGENE (2010)
Hedgehog pathway-regulated gene networks in cerebellum development and tumorigenesis
Eunice Y. Lee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
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Francesca Pistollato et al.
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Identification of CD15 as a Marker for Tumor-Propagating Cells in a Mouse Model of Medulloblastoma
Tracy-Ann Read et al.
CANCER CELL (2009)
Multipotent CD15(+) Cancer Stem Cells in Patched-1-Deficient Mouse Medulloblastoma
Ryan J. Ward et al.
CANCER RESEARCH (2009)
Bmi-1 cooperates with Foxg1 to maintain neural stem cell self-renewal in the forebrain
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Beta-catenin status in paediatric medulloblastomas: correlation of immunohistochemical expression with mutational status, genetic profiles, and clinical characteristics
Sarah Fattet et al.
JOURNAL OF PATHOLOGY (2009)
MicroRNA-199b-5p Impairs Cancer Stem Cells through Negative Regulation of HES1 in Medulloblastoma
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PLOS ONE (2009)
Deletion of Atoh1 Disrupts Sonic Hedgehog Signaling in the Developing Cerebellum and Prevents Medulloblastoma
Adriano Flora et al.
SCIENCE (2009)
Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma
Ulrich Schueller et al.
CANCER CELL (2008)
Medulloblastoma can be initiated by deletion of patched in lineage-restricted progenitors or stem cells
Zeng-Jie Yang et al.
CANCER CELL (2008)
PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo
Dolores Hambardzumyan et al.
GENES & DEVELOPMENT (2008)
Integrated Genomics Identifies Five Medulloblastoma Subtypes with Distinct Genetic Profiles, Pathway Signatures and Clinicopathological Features
Marcel Kool et al.
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Bmi1 Is Required for Hedgehog Pathway-Driven Medulloblastoma Expansion
Lowell E. Michael et al.
NEOPLASIA (2008)
FOXG1 dysregulation is a frequent event in medulloblastoma
Adekunle M. Adesina et al.
JOURNAL OF NEURO-ONCOLOGY (2007)
Wnt/Wingless pathway activation and chromosome 6 loss characterize a distinct molecular sub-group of medulloblastomas associated with a favorable prognosis
Steven C. Clifford et al.
CELL CYCLE (2006)
Wnt/β-catenin signaling in development and disease
Hans Clevers
CELL (2006)
Morphogen to mitogen: the multiple roles of hedgehog signalling in vertebrate neural development
Marc Fuccillo et al.
NATURE REVIEWS NEUROSCIENCE (2006)
Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors
Xing Fan et al.
CANCER RESEARCH (2006)
Genornics identifies medulloblastoma subgroups that are enriched for specific genetic alterations
MC Thompson et al.
JOURNAL OF CLINICAL ONCOLOGY (2006)
Development of the deep cerebellar nuclei: Transcription factors and cell migration from the rhombic lip
AJ Fink et al.
JOURNAL OF NEUROSCIENCE (2006)
β-catenin status predicts a favorable outcome in childhood medulloblastoma:: The United Kingdom Children's Cancer Study Group Brain Tumour Committee
DW Ellison et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
Math1 expression redefines the rhombic lip derivatives and reveals novel lineages within the brainstem and cerebellum
VY Wang et al.
NEURON (2005)
Brain as a paradigm of organ growth: Hedgehog-Gli signaling in neural stem cells and brain tumors
B Stecca et al.
JOURNAL OF NEUROBIOLOGY (2005)
Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice
SWM Bruggeman et al.
GENES & DEVELOPMENT (2005)
Isolation of neural stem cells from the postnatal cerebellum
A Lee et al.
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Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer
GV Glinsky et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
Loss of patched and disruption of granule cell development in a pre-neoplastic stage of medulloblastoma
TG Oliver et al.
DEVELOPMENT (2005)
Cellular and genetic regulation of the development of the cerebellar system
C Sotelo
PROGRESS IN NEUROBIOLOGY (2004)
Medulloblastoma: signalling a change in treatment
RJ Gilbertson
LANCET ONCOLOGY (2004)
Bmi1 is essential for cerebellar development and is overexpressed in human medulloblastomas
C Leung et al.
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Conserved mechanisms across development and tumorigenesis revealed by a mouse development perspective of human cancers
AT Kho et al.
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Stem colls and cancer: The polycomb connection
ME Valk-Lingbeek et al.
CELL (2004)
Identification of human brain tumour initiating cells
SK Singh et al.
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Expression of MATH1, a marker of cerebellar granule cell progenitors, identifies different medulloblastoma sub-types
E Salsano et al.
NEUROSCIENCE LETTERS (2004)
The SmoA1 mouse model reveals that notch signaling is critical for the growth and survival of sonic hedgehog-induced medulloblastomas
AR Hallahan et al.
CANCER RESEARCH (2004)
Notch1 and Notch2 have opposite effects on embryonal brain tumor growth
X Fan et al.
CANCER RESEARCH (2004)
Cancerous stem cells can arise from pediatric brain tumors
HD Hemmati et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
AXIN1 mutations but not deletions in cerebellar medulloblastomas
N Baeza et al.
ONCOGENE (2003)
Nmyc upregulation by sonic hedgehog signaling promotes proliferation in developing cerebellar granule neuron precursors
AM Kenney et al.
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Mutations in SUFU predispose to medulloblastoma
MD Taylor et al.
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Prediction of central nervous system embryonal tumour outcome based on gene expression
SL Pomeroy et al.
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Genetic regulation of cerebellar development
VY Wang et al.
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Direct isolation of human central nervous system stem cells
N Uchida et al.
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Nuclear localization and mutation of β-catenin in medulloblastomas
CG Eberhart et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2000)
APC mutations in sporadic medulloblastomas
HT Huang et al.
AMERICAN JOURNAL OF PATHOLOGY (2000)
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