4.5 Article

THE CLINICAL BURDEN AND PREDICTORS OF SEQUELAE FOLLOWING INVASIVE MENINGOCOCCAL DISEASE IN AUSTRALIAN CHILDREN

期刊

PEDIATRIC INFECTIOUS DISEASE JOURNAL
卷 33, 期 3, 页码 316-318

出版社

LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/INF.0000000000000043

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invasive meningococcal disease; sequelae

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  1. Novartis Vaccines and Diagnostics Pty Ltd

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Of 109 children admitted to a tertiary paediatric hospital with a diagnosis of invasive meningococcal disease from 2000-2011, 37.6% (n = 41) developed sequelae; for serogroup B, 41.3% developed sequelae. Independent predictors of sequelae included: fever 39 degrees C on hospital presentation [odds ratio (OR): 4.5; P = 0.012] and a diagnosis of septicemia with meningitis compared with septicemia alone (OR: 15.5; P < 0.001) and meningitis alone (OR: 7.8; P = 0.002).

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