期刊
PEDIATRIC INFECTIOUS DISEASE JOURNAL
卷 27, 期 11, 页码 1030-1032出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/INF.0b013e31817e5188
关键词
pneumococcus; empyema; invasive disease; pneumococcal vaccine
A retrospective review of medical records for all pediatric parapneumonic empyema (PPE) patients admitted to our hospital from 1996 to 2006 revealed that PPE increased 5-fold in the post-heptavalent pneumococcal conjugate vaccine (PCV7) period (2001-2005) relative to the pre-PCV7 period (1996-2000), from 13 cases to 65. Most of this increase was associated with culture-negative empyema, which accounted for 61% of all post-2000 cases; 19% was culture-positive pneumococcal empyema. Our analysis indicates that,pes became more prevalent at our institution after non-PCV7 serotypes introduction of the vaccine.
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