期刊
PEDIATRIC CRITICAL CARE MEDICINE
卷 12, 期 2, 页码 E94-E98出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/PCC.0b013e3181dde680
关键词
myopathy; nemaline; respiratory insufficiency; muscle weakness; respiratory muscles; strength training; organ transplantation
资金
- National Institutes of Health [T32 HD043730A]
- Foundation for Physical Therapy
Objective: To report the use of inspiratory muscle strength training to treat repeated ventilatory insufficiency in a child with nemaline myopathy who underwent cardiac and renal transplantation. Design: Case report. Setting: Pediatric intensive care unit of a tertiary care university teaching hospital. Patient: A 16-yr-old female with nemaline myopathy affecting cardiorespiratory function, recent organ transplantation, and delayed postoperative ventilatory recovery. Intervention: Inspiratory muscle strength training was provided 5 days weekly for 2 wks, accompanied by progressive weaning from noninvasive ventilation. Measurements and Main Results: Maximal inspiratory pressure increased from -36.7 cm H2O to -77.8 cm H2O, accompanied by improved inspiratory flow, volume, pressure activation and power. During the training period, the patient was weaned from continuous noninvasive ventilatory assist to her preoperative level of ventilatory function. Conclusion: Inspiratory muscle training may be a beneficial component of care for children with nemaline myopathy who experience acute ventilatory insufficiency. (Pediatr Crit Care Med 2011; 12:e94-e98)
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